2001-2019 年波多黎各近期宫颈癌发病率、诊断分期和死亡率趋势。
Recent cervical cancer incidence, stage at diagnosis, and mortality trends in Puerto Rico, 2001-2019.
发表日期：2024 Aug 13
作者：
Ana P Ortiz, Carlos R Torres-Cintrón, Eduardo J Santiago-Rodríguez, Jeslie M Ramos-Cartagena, Tonatiuh Suárez-Ramos, Haluk Damgacioglu, Vivian Colón-López, Karen J Ortiz-Ortiz, Ashish A Deshmukh
来源：
BMC Medicine
摘要：
波多黎各 (PR) 的宫颈癌发病率正在上升。这种增加是真实的还是反映了诊断审查的增加仍不清楚。使用 PR 中央癌症登记处 2001-2019 年的数据，我们估计了子宫切除术校正的宫颈癌总体发病率和死亡率的趋势，以及按诊断阶段和年龄划分的趋势总体而言，宫颈癌发病率（每 100,000 人）每年增加 1.6%（95% CI，-0.5% 至 3.8%），从 12.5 增加至 15.3，其中晚期疾病显着增加（4.5%/年 [95% CI ，1.6% 至 8.0%]），特别是在符合筛查年龄（25-64 岁）的女性中（5.8%/年 [95% CI，2.1% 至 10.6%]）。在研究期间，该年龄组的死亡率保持稳定。符合筛查资格的女性中远期疾病发生率的增加令人不安，可能反映了实际的增加。需要未来的研究来阐明这些趋势背后的因素。改善预防也是扭转 PR 中宫颈癌发病率上升的当务之急。© 2024。作者。
Cervical cancer incidence is rising in Puerto Rico (PR). Whether the increase is real or reflective of increased diagnostic scrutiny remains unclear.Using data from the PR Central Cancer Registry for 2001-2019, we estimated trends of hysterectomy-corrected cervical cancer incidence and mortality rates, overall, and by stage at diagnosis and age.Overall, cervical cancer incidence (per 100,000) increased 1.6%/year (95% CI, -0.5% to 3.8%) from 12.5 to 15.3, with a prominent increase in distant-stage disease (4.5%/year [95% CI, 1.6% to 8.0%]), particularly among screening age eligible (25-64-year-old) women (5.8%/year [95% CI, 2.1% to 10.6%]). Mortality rates in this age-group remained stable during the study period.Increased occurrence of distant-stage disease among screening-eligible women is troubling and may reflect a real increase. Future research is needed to elucidate the factors underlying these trends. Improved prevention is also an urgent priority to reverse the rising cervical cancer incidence in PR.© 2024. The Author(s).