人类肠道微生物群 (GM) 会影响各种生理过程，如果体内平衡被破坏，可能会导致病理状况甚至致癌。最近的研究表明转基因与前列腺疾病之间存在联系。然而，其根本机制仍不清楚。本综述旨在总结有关 GM 与各种前列腺疾病（如慢性前列腺炎/慢性盆腔疼痛综合征 (CP/CPPS)、良性前列腺增生 (BPH) 和前列腺癌 (PCa)）之间联系的现有信息。此外，该综述旨在确定可能的致病机制，并提出针对转基因预防和治疗前列腺疾病的潜在方法。由于转基因与前列腺疾病之间机制的复杂性，需要更多的研究来理解两者之间的关联。这将为前列腺疾病带来更有效的治疗选择。版权所有 © 2024 Cao、Zhang、Wang、Wang、Shi、Wu、Du、Zhang、Gou、Zhou 和 Wang。

The human gut microbiome (GM) impacts various physiological processes and can lead to pathological conditions and even carcinogenesis if homeostasis is disrupted. Recent studies have indicated a connection between the GM and prostatic disease. However, the underlying mechanisms are still unclear. This review aims to provide a summary of the existing information regarding the connection between the GM and various prostatic conditions such as chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS), benign prostatic hyperplasia (BPH), and prostate cancer (PCa). Furthermore, the review aims to identify possible pathogenic mechanisms and suggest potential ways of targeting GM to prevent and treat prostatic disease. Due to the complexity of the mechanism between GM and prostatic diseases, additional research is required to comprehend the association between the two. This will lead to more effective treatment options for prostatic disease.Copyright © 2024 Cao, Zhang, Wang, Wang, Shi, Wu, Du, Zhang, Gou, Zhou and Wang.