人工智能对药物开发和交付的影响。
Impact of Artificial Intelligence on Drug Development and Delivery.
发表日期：2024 Aug 12
作者：
Chintan Aundhia, Ghanshyam Parmar, Chitrali Talele, Niyati Shah, Dipali Talele
来源：
BIOSENSORS & BIOELECTRONICS
摘要：
这篇综述探讨了人工智能对制药科学中药物开发和递送的变革性影响，涵盖配方设计、实时监测、靶向递送和未来前景。智能药物载体的合理设计，例如用于癌症治疗的人工智能优化脂质体，可以根据患者的个体需求优化配方。人工智能驱动的传感器（以糖尿病患者的血糖监测生物传感器为例）可以实现自适应药物管理，从而提高精确度。尽管做出了承诺，但生物相容性、法规和道德等挑战仍然存在。跨学科协作和透明沟通对于负责任的人工智能采用至关重要。预期趋势包括个性化剂量优化和智能纳米载体。该评论强调了人工智能重塑药物以实现以患者为中心的护理的潜力，同时解决了广泛采用的挑战。版权所有© Bentham Science Publishers；如有任何疑问，请发送电子邮件至 epub@benthamscience.net。
This review explores the transformative impact of AI on drug development and delivery in pharmaceutical sciences, spanning formulation design, real-time monitoring, targeted delivery, and future prospects. The rational design of smart drug carriers, such as AI-optimized liposomes for cancer therapy, optimizes formulations for individual patient needs. AI-driven sensors, exemplified by glucose-monitoring biosensors for diabetics, enable adaptive drug administration, enhancing precision. Despite promises, challenges like biocompatibility, regulations, and ethics persist. Interdisciplinary collaboration and transparent communication are crucial for responsible AI adoption. Anticipated trends include personalized dosage optimization and intelligent nanocarriers. The review underscores AI's potential in reshaping pharmaceuticals for patient-centric care while addressing challenges for widespread adoption.Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.