使用定性和定量方法探讨影响乳腺癌化疗期间和化疗后参加生活方式干预的参与者采用基于指南的体力活动 (PA) 和饮食建议的因素。在诊断后早期生活方式、运动和营养 (LEANer) 试验的干预部分，我们使用分层、有目的的抽样来采访在 1 年干预后达到两个、一个或两个干预目标的女性：(1) 150 分钟每周通过自我报告的 PA 问卷进行中等至剧烈强度的锻炼，以及 (2) 通过 2015 年健康饮食指数衡量，改善自我报告的饮食质量。半结构化访谈进行录音、逐字转录，并使用主题内容分析进行分析。受访的 29 名女性平均年龄为 52±11 岁，平均体重指数为 29.6±7.7 kg/m2。关于促进行为改变的 LEAner 干预措施，出现了三个主题：(1) 提供值得信赖、及时和个性化的支持和教育渠道； (2) 转变观念并加深对化疗期间 PA 和营养益处的理解； (3) 培养控制感和替代焦点。被描述为阻碍目标采用的因素包括：(1) 化疗的不利影响和 (2) 相互竞争的优先事项。女性报告称，外部支持、量身定制的教育以及体验 LEAner 干预措施对身心的好处促进了干预措施的采用。行为目标。解决化疗相关症状和竞争优先事项可能有助于乳腺癌化疗期间坚持生活方式干预。© 2024。作者获得 Springer-Verlag GmbH 德国（Springer Nature 旗下公司）的独家许可。

Use qualitative and quantitative methods to explore factors influencing the adoption of guideline-based physical activity (PA) and dietary recommendations among participants enrolled in a lifestyle intervention during and after chemotherapy for breast cancer.Among women with stage I-III breast cancer who participated in the intervention arm of the Lifestyle, Exercise, and Nutrition early after diagnosis (LEANer) trial, we used stratified, purposeful sampling to interview women who met both, one, or neither intervention goal after the 1-year intervention: (1) 150 min/week moderate-to-vigorous intensity exercise via a self-reported PA questionnaire and (2) improved self-reported diet quality measured by the Healthy Eating Index-2015. Semi-structured interviews were audio-recorded, transcribed verbatim, and analyzed using thematic content analysis.The 29 women interviewed were 52 ± 11 years old on average, with a mean body mass index of 29.6 ± 7.7 kg/m2. Three themes emerged regarding aspects of the LEANer intervention that facilitated behavior change: (1) providing a conduit of trustworthy, timely, and personalized support and education; (2) shifting mindsets and enhanced understanding of the benefits of PA and nutrition during chemotherapy; and (3) fostering a sense of control and alternative focus. Factors described as hindering adoption of goals included: (1) adverse effects of chemotherapy and (2) competing priorities.Women reported the external support, tailored education, and experiencing the physical and mental benefits of the LEANer intervention facilitated the adoption of the interventions' behavioral goals. Addressing chemotherapy-related symptoms and competing priorities may facilitate adherence to lifestyle interventions during chemotherapy for breast cancer.© 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.