比较 CEUS 引导活检 (CEUS-GB) 和超声引导活检 (US-GB) 在评估儿科患者腹部和盆腔（腹盆腔）肿瘤方面的诊断性能。年龄 < 18 岁的腹盆腔肿瘤接受 CEUS 的患者-对2005年4月至2022年5月期间的GB或US-GB进行回顾性评估。通过病理学诊断为恶性肿瘤的肿瘤被认为是真阳性结果。通过至少 6 个月的病理学或临床随访发现良性病变。使用倾向评分匹配（PSM）比较两组的诊断表现。还分析了并发症。本研究纳入了 764 名儿科患者（437 名男孩；中位年龄为 24 个月；四分位数范围为 10-60 个月）； CEUS-GB 组有 151 例，US-GB 组有 613 例。 CEUS-GB 组的样本充足率为 100%（151 例中的 151 例），高于 US-GB 组的 97.4%（613 例中的 597 例）（p<0.001）。总队列中，CEUS-GB 组和 US-GB 组的总体诊断准确度分别为 98.7%（151 人中的 149 人）与 97.3%（597 人中的 581 人）（p = 0.551）和 98.7%（151 人中的 149 人）与 92.7 PSM 队列中的 %（151 中的 140）（p = 0.020）。 US-GB 组中的两名患者 (0.3%) 出现了与活检相关的并发症（不良事件通用术语标准 (CTCAE)，1-2 级）。 CEUS-GB组未出现不良反应。CEUS-GB治疗儿科腹盆腔肿瘤是一种有效、安全的手术，其诊断准确性比US-GB更高，特别是对于有坏死区域的肿瘤。超声引导下超声造影活检儿科患者腹部和盆腔实性肿瘤是一种有效且安全的手术，其诊断准确性比超声引导的活检更高，尤其是对于有坏死区域的肿瘤。超声造影 (CEUS) 在引导腹部盆腔肿块活检方面可能优于传统超声在儿科患者中。 CEUS 引导下的儿童腹盆腔肿块粗针活检是安全的，诊断率为 98.7%。当彩色多普​​勒超声无法确定活检部位时，应在该人群中考虑 CEUS 指导。© 2024。作者，获得欧洲放射学会的独家许可。

To compare the diagnostic performance of CEUS-guided biopsy (CEUS-GB) and ultrasound-guided biopsy (US-GB) in evaluating abdominal and pelvic (abdominopelvic) neoplasms in paediatric patients.Patients aged < 18 years with abdominopelvic tumours who underwent either CEUS-GB or US-GB between April 2005 and May 2022 were retrospectively evaluated. Tumours diagnosed as malignancies by pathology were considered true-positive findings. Benign lesions were identified by pathology or clinical follow-up of at least 6 months. The diagnostic performance of the two groups was compared using propensity score matching (PSM). Complications were also analysed.The present study included 764 paediatric patients (437 boys; median age, 24 months; interquartile range, 10-60 months); 151 were in the CEUS-GB group, and 613 were in the US-GB group. The sample adequacy rate was 100% (151 of 151) for the CEUS-GB group, which was greater than the 97.4% (597 of 613) for the US-GB group (p < 0.001). The overall diagnostic accuracy of the CEUS-GB group and US-GB group was 98.7% (149 of 151) versus 97.3% (581 of 597) in the total cohort (p = 0.551) and 98.7% (149 of 151) versus 92.7% (140 of 151) in the PSM cohort (p = 0.020). Two patients (0.3%) in the US-GB group experienced complications (Common Terminology Criteria for Adverse Events (CTCAE), grade 1-2) correlated with the biopsy. No adverse reactions occurred in the CEUS-GB group.CEUS-GB of abdominopelvic tumours in paediatric patients is an effective and safe procedure with greater diagnostic accuracy than US-GB, especially for tumours with necrotic areas.Contrast-enhanced US-guided biopsy of solid abdominal and pelvic tumours in paediatric patients is an effective and safe procedure with greater diagnostic accuracy than US-guided biopsy, especially for tumours with necrotic areas.Contrast-enhanced ultrasound (CEUS) may be superior to conventional ultrasound at guiding biopsy of abdominopelvic masses in paediatric patients. CEUS-guided core needle biopsy of abdominopelvic masses in children was safe and resulted in a diagnostic yield of 98.7%. CEUS guidance should be considered in this population when colour Doppler US is unable to determine a biopsy site.© 2024. The Author(s), under exclusive licence to European Society of Radiology.