在本研究中，对大白菜（Brassica rapa L. ssp. pekinensis）根进行溶剂分级，并研究其抗氧化和抗炎作用。抗氧化能力（DPPH 和 ABTS 自由基、氧自由基吸收能力和铜还原抗氧化能力）在乙酸乙酯馏分 (CREE) 中最高，分别为 26.74、69.81、253.23 和 54.77 mg TEAC/g。在用脂多糖 (1 µg/mL) 刺激的 RAW 264.7 细胞中评估炎症反应。 CREE 使一氧化氮和前列腺素 E2 分别降低 53.37% 和 16.30%。促炎细胞因子如肿瘤坏死因子-α、白细胞介素-1β和白细胞介素-6分别被抑制36.85%、62.99%和54.78%。此外，诱导型一氧化氮合酶、环氧合酶-2 和白介素-6 基因分别被抑制 43.38%、24.23% 和 80.85%。结果表明，CREE 具有抗氧化和抗炎作用。© 韩国食品科学技术学会 2024。Springer Nature 或其许可方（例如协会或其他合作伙伴）根据出版协议拥有本文的独家权利与作者或其他权利持有人；作者对本文已接受手稿版本的自行存档仅受此类出版协议条款和适用法律的约束。

In this study, Chinese cabbage (Brassica rapa L. ssp. pekinensis) roots were solvent fractioned, and their antioxidant and anti-inflammatory effects were investigated. The antioxidant capacity (DPPH and ABTS radicals, oxygen radical absorbance capacity, and cupric reducing antioxidant capacity) was the highest in the ethyl acetate fraction (CREE) at 26.74, 69.81, 253.23, and 54.77 mg TEAC/g, respectively. The inflammatory responses were evaluated in RAW 264.7 cells stimulated with lipopolysaccharide (1 µg/mL). CREE decreased nitric oxide and prostaglandin E2 by 53.37% and 16.30%, respectively. Pro-inflammatory cytokines such as tumor necrosis factor-α, interleukin-1β, and interleukin-6 were inhibited by 36.85%, 62.99%, and 54.78%, respectively. Furthermore, inducible nitric oxide synthase, cyclooxygenase-2, and interleukin-6 genes were inhibited by 43.38%, 24.23%, and 80.85%, respectively. The results suggest that CREE is responsible for its antioxidant and anti-inflammatory effects.© The Korean Society of Food Science and Technology 2024. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.