尽管肺癌筛查和治疗不断取得进展，但肺癌仍然是美国和全世界癌症死亡的最常见原因。高达 50% 的癌症死后患者发现心包积液 (PerF)；肺癌和乳腺癌是最常见的恶性肿瘤。此外，这是生存期不足 5 个月的不良结果的迹象。然而，伴或不伴填塞的 PErF 作为肺癌的表现并不常见。我们介绍了一名无病史的 72 岁男性，他出现咳嗽 1 个月，伴有白色痰和呼吸急促，病情逐渐恶化，并伴有体重减轻（20 磅）。进一步的研究表明，早期心脏压塞继发于恶性肿瘤。心脏压塞可以由各种病因继发，并且根据病因有不同的表现。一般来说，这是一个缓慢发展且临床上无症状的疾病过程。因此，恶性 PerF 很少会出现血流动力学不稳定，并且是潜在恶性肿瘤的最初表现。我们的病例回顾介绍了一个罕见的转移性肺腺癌病例，表现为早期症状性心包填塞和紧急情况。如果此演示未得到适当识别和管理，结果可能会危及生命。临床医生必须意识到胸部恶性肿瘤的这种非典型表现，才能采取充分的行动。© 2024 作者。由巴塞尔 S. Karger AG 出版。

Lung cancer remains the most common cause of cancer death in the USA and worldwide despite continued advances in lung cancer screening and treatment. Pericardial effusion (PerF) has been found in up to 50% of postmortem patients with cancer; lung and breast cancers are the most frequent malignancies. Furthermore, it is a sign of poor outcomes with fewer than 5 months of survival. Nevertheless, PErF with or without tamponade as a presentation of lung cancer is uncommon.We present a 72-year-old male without medical history who presented with 1 month of cough with white sputum and shortness of breath, progressively worsening, associated with weight loss (20 pounds). Further studies demonstrated early cardiac tamponade secondary to malignancy.Cardiac tamponade can arise secondarily from various etiologies and have different presentations depending on the cause. In general, it is a slowly developing and clinically silent disease process. Therefore, malignant PerFs can rarely present with hemodynamic instability and be the initial manifestation of an underlying malignancy. Our case review presents a rare case of metastatic lung adenocarcinoma manifesting as early symptomatic cardiac tamponade and as an emergency. The results might be life-threatening if this presentation is not recognized and managed appropriately. Clinicians must be aware of such atypical presentations of thoracic malignancies to take action adequately.© 2024 The Author(s). Published by S. Karger AG, Basel.