本研究文章的目的是调查各种健康史因素对患帕金森病 (PD) 风险的影响。从病史中我们可以识别帕金森病症状，这也有助于检测帕金森病症状的进展。通过进行统计分析，该研究试图确定帕金森病 (PD) 的独立风险和保护因素，同时考虑性别和 BMI 类别之间影响的差异。在 PD 的诊断中，对既往健康史的分析在实践中很少见，而主要诊断是通过不同的运动和非运动症状来完成的，除了PD的主要症状外，还考虑到PD的识别​​和阶段确定。在这里，我们分析了受试者在 PD 之前可能经历过的 56 种不同疾病、症状和手术的影响，将其视为健康史。已对 31,265 名受试者进行了统计分析，包括PD 和控制。在这项分析中，我们计算了男性和女性以及 BMI.98.12% PD 患者的影响变化，其中 97.63% 男性 PD 和 98.71% 女性 PD 至少有一份健康史记录。冠心病比值比（OR）2.15（1.85-2.51）、结肠癌OR 2.11（1.45-3.05）、颅脑手术OR 6.21（5.11-7.56）PD风险较高。有哮喘病史 OR 0.66 (0.6-0.72)、贫血病史 OR 0.56 (0.51-0.63)、肝硬化病史 OR 0.7 (0.57-0.86)、整容手术病史 OR 0.7 (0.64-0.77) 和胃炎病史 OR 0.78 (0.71-0.71) 0.87）已被发现对PD有保护作用。男性和女性患 PD 的风险各不相同，包括每个个体健康史类型的受试者 BMI。贫血、哮喘和地中海贫血等降低血液中氧饱和度的疾病对帕金森病具有保护作用。在这项研究中，我们分析了包括手术在内的 56 种疾病作为帕金森病患者的健康史。研究表明，完整的健康史可以极大地帮助了解帕金森病 (PD) 的发病和进展。© 2024 作者。

The objective of this research article is to investigate the impact of various health history factors on the risk of developing Parkinson's disease (PD). From the medical history we can identify PD Symptoms and this also help to detect the progression of PD symptoms. By conducting statistical analyses, the study seeks to identify independent risk and protective factors for Parkinson's disease (PD), considering variations in impact across genders and BMI categories.In the diagnosis of PD the analysis of previous health history is very rare in practice while the main diagnosis have been done through the different motor and non-motor symptoms taking in consideration besides the cardinal symptoms of PD for identification and determination the stages of PD. Here we have analyzed the impact of 56 different diseases, symptoms, and surgeries which a subject may have experienced in their life before PD, considered as a health history.The behavioral impact for each types of health history have been analyzed statistically with 31,265 subjects including PD, and Control. In this analysis we have calculated the variation of impact for both the Male, and Female, as well as subjects BMI.98.12 % PD patients, where 97.63 % Male PD, and 98.71 % Female PD were found with at least one health history record. Coronary heart disease odds ratio (OR) 2.15 (1.85-2.51), Colon Cancer OR 2.11 (1.45-3.05), Cranial brain surgery OR 6.21 (5.11-7.56) have the higher risks to PD. Having the history of Asthma OR 0.66 (0.6-0.72), Anemia OR 0.56 (0.51-0.63), Cirrhosis in Liver OR 0.7 (0.57-0.86), Cosmetic surgery OR 0.7 (0.64-0.77), and Gastritis OR 0.78 (0.71-0.87) have been found to be protective to PD. The risk of developing PD varies between male, and female including subjects BMI for each individual health history types. The diseases which reduce the oxygen saturation in blood like, anemia, asthma, and thalassemia act as protective to PD.In this study we have analyzed fifty six diseases which include surgeries as a health history of PD patients. Study suggests that a thorough health history could greatly aid in understanding the onset and progression of Parkinson's disease (PD).© 2024 The Authors.