纤维脂肪瘤被定义为被不同数量的稀细胞和胶原纤维成分横切的典型脂肪瘤。口腔和舌纤维脂肪瘤是人类医学中公认的组织学实体，在女性中稍微普遍，最常见于四十几岁之后，并且起源于颊粘膜。兽医学中缺乏这种口腔肿瘤的记录。通过对提交给诊断病理学服务的病例进行多机构回顾性汇编，我们在此描述了犬口腔纤维脂肪瘤的临床和病理特征。共检索犬口腔纤维脂肪瘤112例。平均年龄为 10.1 岁（范围 2-16 岁，±2.63 岁标准差），平均肿瘤大小为 1.7 cm（范围 0.2-8 cm，±1.1 cm 标准差）。最常见的部位是舌头（57.1%，64/112），其次是颊粘膜（15.2%，16/112）、舌下区（8.0%，9/112）、牙龈和唇（4.5%，5/各 112 个）和味觉（1 箱）。口腔纤维脂肪瘤的解剖位置仅在犬种之间存在显着差异（P < .001），但在性别、年龄、既往史或提交原因之间没有显着差异。该肿瘤最常见于男性 (69.7%, 78/112)，并且在 62.5% (70/112) 的病例中，肿瘤是偶然发现的。当考虑狗的良性舌和其他口腔软组织肿块时，纤维脂肪瘤应被视为鉴别诊断。

Fibrolipoma is defined as a typical lipoma transected by variable amounts of paucicellular and collagenous fibrous components. Oral and lingual fibrolipomas are well-recognized histological entities in human medicine that are slightly more prevalent in females, occur most commonly after the fourth decade, and arise from the buccal mucosa. The documentation of this neoplasm in the oral cavity is lacking in veterinary medicine. Through a multi-institutional retrospective compilation of cases submitted to diagnostic pathology services, here we describe the clinical and pathologic features of oral fibrolipomas in dogs. A total of 112 cases of oral fibrolipomas in dogs were retrieved. The mean age was 10.1 years (range 2-16 years, ±2.63 years standard deviation), with an average tumor size of 1.7 cm (range 0.2-8 cm, ±1.1 cm standard deviation). The most common location was the tongue (57.1%, 64/112), followed by the buccal mucosa (15.2%, 16/112), sublingual area (8.0%, 9/112), gingiva and lip (4.5%, 5/112 each), and palate (1 case). The anatomical location of oral fibrolipomas only differed significantly among the dog breeds (P < .001) but not among sex, age, anamnesis, or reason for submission. The tumor was most commonly reported in males (69.7%, 78/112), and in 62.5% (70/112) of the cases, the tumor was an incidental finding. Fibrolipoma should be considered a differential diagnosis when considering benign lingual and other oral soft tissue masses in dogs.