创伤和癌症是美国的主要原因。描述癌症对创伤患者影响的数据很少。我们的目的是确定癌症对创伤患者结局的影响。在美国外科医生学会 2019-2021 年创伤质量改进计划的回顾性分析中，我们纳入了所有成年创伤患者（≥18 岁），并排除了严重头部损伤的患者和非黑色素瘤皮肤癌。患者被分为癌症 (C) 和非癌症 (No-C)。进行倾向评分匹配（1:3）。结果是并发症和死亡率。对 3236 名患者（C，809；No-C，2427）的匹配队列进行了分析。平均年龄为 70 岁，50.5% 为男性，伤害严重程度评分中位数为 8 (4-10)。在接受血栓预防方面没有差异（C 51%：No-C 50%，P = 0.516）。与No-C组相比，C组深静脉血栓发生率较高（C组为1.1% vs No-C组为0.3%，P = 0.004），但总体并发症情况无差异。 C 组患者的死亡率较高（C 组为 7.5%，No-C 组为 2.7%，P < 0.001）。患有癌症的外伤患者发生深静脉血栓的几率高出近 4 倍，死亡率高出 3 倍。开发针对癌症患者的特异性途径可能对于改善患有癌症的创伤患者的预后是必要的。版权所有 © 2024 Elsevier Inc. 保留所有权利。

Trauma and cancer are the leading causes of death in the US. There is a paucity of data describing the impact of cancer on trauma patients. We aimed to determine the influence of cancer on outcomes of trauma patients.In this retrospective analysis of American College of Surgeons-Trauma Quality Improvement Program 2019-2021, we included all adult trauma patients (≥18 y) and excluded patients with severe head injuries and nonmelanomatous skin cancers. Patients were stratified into cancer (C), and no cancer (No-C). Propensity score matching (1:3) was performed. Outcomes were complications and mortality.A matched cohort of 3236 patients (C, 809; No-C, 2427) was analyzed. The mean age was 70 y, 50.5% were males, and the median injury severity score was 8 (4-10). There were no differences in terms of receiving thromboprophylaxis (C 51%: No-C 50%, P = 0.516). Compared to No-C group, the C group had higher rates of deep vein thrombosis (C 1.1% versus No-C 0.3%, P = 0.004), but there was no difference in terms of overall complications. Patients in the C group had higher mortality (C 7.5% versus No-C 2.7%, P < 0.001).Trauma patients with cancer have nearly 4 times higher odds of deep vein thrombosis and 3 times higher odds of mortality. Developing pathways specific to cancer patients might be necessary to improve the outcomes of trauma patients with cancer.Copyright © 2024 Elsevier Inc. All rights reserved.