乳腺癌肺转移发生率高、早期，是乳腺癌患者死亡的主要原因。本研究旨在探讨乳癌舒厚方（RSR）干预对乳腺癌术后患者复发转移尤其是肺转移发生的影响。在上海大学曙光医院进行回顾性队列研究2014年1月至2019年1月中国中医杂志。根据倾向评分匹配（PSM）方法纳入女性患者，并根据年龄、体重指数、新辅助治疗、和手术方法。本研究纳入病理诊断为乳腺癌的患者。乳腺癌患者根据手术后是否服用基于RSR的植物药物分为暴露组和非暴露组。 Kaplan-Meier生存分析和Cox生存分析探讨乳腺癌患者术后RSR与5年无病生存和肺转移发生率的关系。对360名女性患者进行了评估，PSM后190名患者纳入研究（暴露组和非暴露组各 95 个）。在 PSM 后的 190 名患者中，55.79% 的年龄超过 50 岁。暴露组的平均随访时间为 60.55 ± 14.82 个月，非暴露组为 57.12 ± 16.37 个月。两组之间没有显着的基线特征差异。 Kaplan-Meier分析显示，暴露组5年肺转移发生率明显较低，患者无病生存期明显较长。 Cox单因素和多因素分析显示，新辅助化疗和淋巴结转移是乳腺癌发生肺转移的独立危险因素，风险比分别为17.188和5.812，而RSR治疗是乳腺癌发生肺转移的独立保护因素。 ，风险比为0.290。标准生物医学治疗结合RSR干预可以更好地预防乳腺癌复发和转移，降低患者肺转移发生率，改善长期预后。Copyright © 2024 杜邵冯万和吴。

Breast cancer lung metastasis occurs at a high rate and at an early stage, and is the leading cause of death in breast cancer patients. The aim of this study was to investigate the effect of Ru'ai Shuhou Recipe (RSR) intervention on the occurrence of recurrent metastases, especially lung metastases, in postoperative patients with breast cancer.A retrospective cohort study was implemented at Shuguang Hospital of Shanghai University of Traditional Chinese Medicine in China between January 2014 to January 2019. Female patients were included according to the propensity score matching (PSM) method and balanced on the basis of general and clinical information such as age, body mass index, neo-adjuvant therapy, and surgical approach. Patients with pathological diagnosis of breast cancer were included in this study. Breast cancer patients were divided into exposed and non-exposed groups according to whether they took RSR-based botanical drugs after surgery. Kaplan-Meier survival analysis and Cox survival analysis to explore the relationship between RSR and 5-year disease-free survival and incidence of lung metastases in breast cancer patients after surgery.360 female patients were assessed and 190 patients were included in the study after PSM (95 in each of the exposed and non-exposed groups). Of the 190 patients after PSM, 55.79% were over 50 years of age. The mean follow-up time was 60.55 ± 14.82 months in the exposed group and 57.12 ± 16.37 months in the non-exposed group. There was no significant baseline characteristics difference between two groups. Kaplan-Meier analysis showed that the 5-year incidence of lung metastases was significantly lower in the exposed group, and the disease-free survival of patients was significantly longer. Cox univariate and multivariate analysis showed that neoadjuvant chemotherapy and lymph node metastasis were independent risk factors for the development of breast cancer lung metastasis, with risk ratios of 17.188 and 5.812, while RSR treatment was an independent protective factor against the development of breast cancer lung metastasis, with a risk ratio of 0.290.Standard biomedical treatment combined with RSR intervention can better prevent breast cancer recurrence and metastasis, reduce the incidence of lung metastasis in patients, and improve long-term prognosis.Copyright © 2024 Du, Shao, Feng, Wan and Wu.