结直肠癌是一种高度流行的恶性肿瘤，也是全球癌症死亡率和健康相关支出的重要驱动因素。息肉切除可降低结直肠癌的发病率和死亡率。到 2024 年，内窥镜医师将拥有多种切除方式可供选择。每种技术都需要独特的技能，并且具有各自的优点和局限性。因此，结直肠切除术需要一种考虑这些因素的基于证据的算法方法。对结肠肿瘤内镜切除术进行了文献综述。总结了内镜切除小型息肉、≥20 毫米大病变和含有浸润性癌息肉的最佳支持科学证据。探讨了切除方式、并发症和病灶选择等因素，以指导结直肠切除的算法方法。结直肠内镜切除术并不是一种万能的方法。对息肉大小、位置、形态和预测组织学的详细了解是指导适当内镜切除实践的关键因素。© 2024 S. Karger AG，巴塞尔。

Colorectal cancer is a highly prevalent malignancy and a significant driver of cancer mortality and health-related expenditure worldwide. Polyp removal reduces the incidence and mortality of colorectal cancer. In 2024, endoscopists have an array of resection modalities at their disposal. Each technique requires a unique skillset and has individual advantages and limitations. Consequently, resection in the colorectum requires an evidence-based algorithm approach that considers these factors.A literature review of endoscopic resection for colonic neoplasia was conducted. Best supporting scientific evidence was summarized for the endoscopic resection of diminutive polyps, large ≥20 mm lesions and polyps containing invasive cancer. Factors including resection modality, complications and lesion selection were explored to inform an algorithm approach to colorectal resection.Endoscopic resection in the colorectum is not a one-size-fits-all approach. Detailed understanding of polyp size, location, morphology and predicted histology are critical factors that inform appropriate endoscopic resection practice.© 2024 S. Karger AG, Basel.