下咽区鳞状细胞癌是一种罕见的侵袭性疾病，预后不良，死亡率高，占所有下咽肿瘤的 95%。上呼吸消化道肿瘤患者在放化疗前或放化疗期间可能会出现气道损害。本研究旨在探讨晚期下咽鳞状细胞癌患者择期气管切开术与紧急气管切开术的并发症差异。研究组包括 36 名患者，分析了所有患者在 3 个特定时间点（气管切开前、放射治疗期间以及放射治疗完成后至少 3 个月）的并发症数量和类型、功能结果以及实验室检查的比较。 。此外，还进行了单变量分析以评估局部控制率的预后。择期气管切开术和急诊气管切开术的并发症类型和数量有所不同，但所有并发症均得到解决，未发生气管切开导管移位继发的缺氧并发症或与气管切开相关的死亡病例。共有 20/36 名患者出现并发症，其中 73%（16 名患者）来自紧急气管切开组，36%（4 名患者）来自择期气管切开组。超过一半的选择性气管切开术患者（6/11 例患者）对治疗反应良好，频率高于紧急气管切开术患者（5/22 例患者）。本研究未发现气管切开类型的治疗最终结果存在显着统计学差异（P>0.05），但预测分析发现，对于60岁以下的患者，选择性气管切开术与较高的机会相关。有利的治疗最终结果。版权所有：© 2024 Vulcu Cordunianu 等人。

Squamous cell carcinoma of the hypopharyngeal region is a rare, aggressive disease with a poor prognosis and a high mortality rate, and represents up to 95% of all hypopharyngeal tumors. Patients with upper aerodigestive tract tumors can develop airway compromise before or during chemoradiotherapy. The present study aims to investigate the complication differences between elective tracheostomy and emergency-setting tracheostomy for patients with advanced hypopharyngeal squamous cell. The study group included 36 patients and analyzed the number and type of complications, functional outcomes and comparation of the laboratory testing in all the patients at 3 specific points (before tracheotomy, during the radiation therapy and at least 3 months after completion of radiation therapy). In addition, univariate analysis was performed in order to evaluate the prognosis of local control rates. The type and number of complications between elective and emergency-setting tracheostomy varied, but all the complications were resolved, and no hypoxic complications secondary to displacement of the tracheostomy tube or death cases related to the tracheostomy occurred. A total of 20/36 patients presented with complications, with 73% (16 patients) from the emergency tracheostomy cohort and 36% (4 patients) from the elective tracheostomy group. More than half of the elective tracheostomy (6/11 patients) responded favorably to the treatment, with a higher frequency than the patients with emergency tracheostomy (5/22 patients). The present study did not encounter significant statistical differences (P>0.05) of the treatment end-result regarding the type of tracheostomy performed, but the prediction analysis found for the patients aged under 60 years old, elective tracheostomy was associated with a higher chance of favorable treatment end result.Copyright: © 2024 Vulcu Cordunianu et al.