右结肠癌腹腔镜 D3 淋巴结切除术标准化的提案。
Proposal for standardization of laparoscopic D3 lymphadenectomy for right colon cancer.
发表日期:2024 Aug 20
作者:
Á Garcia-Granero, A Gil-Catalán, S Jerí-McFarlane, J Sancho-Muriel, G Pellino, M Gamundí-Cuesta, E Garcia-Granero, F X Gonzalez-Argenté
来源:
Techniques in Coloproctology
摘要:
本研究提出了右结肠癌右半结肠切除术和 D3 淋巴结切除术 (R-D3L) 的腹腔镜手术方案,并根据前瞻性系列报告了肿瘤学结果。该研究分为两个阶段。第一阶段通过文字解释、插图和编辑的手术视频动态演示R-D3L手术方案。该协议强调技术步骤,例如右结肠系膜胚胎平面的解剖、回结肠血管的高领带、Gillot 解剖的手术干和上右结肠静脉 (SRCV) 的高领带。在第二阶段,进行了一项前瞻性观察性研究,涉及 2015 年 7 月至 2021 年 7 月期间接受该方案的 R-D3L 手术的患者。分析了人口统计学、围手术期和术后变量,以及解剖病理学变量和肿瘤学结果。总共 33对患者进行了分析。中位手术时间为 202 分钟。围手术期出血发生率为 6%。术后并发症轻微(Clavien-Dindo III 为 2%)。术后肠梗阻发生率为 15%。没有吻合口裂开的报道。术后住院时间中位数为 7 天。切除的淋巴结中位数为 26 个,其中 27% 有阳性淋巴结,70% 属于 T3 或 T4 期。中位随访 45 个月后,局部复发、远处复发和癌变率均为 0%。其他原因导致的死亡率为 9%。本研究中显示的手术方案有助于在那些认为合适的单位实施该技术。© 2024。Springer Nature Switzerland AG。
This study presents a laparoscopic surgical protocol for right hemicolectomy and D3 lymphadenectomy (R-D3L) in right colon cancer and reports the oncological outcomes based on a prospective series.The study comprises two phases. In the first phase, a dynamic demonstration of the R-D3L surgical protocol is provided through textual explanation, illustrations, and edited surgical videos. The protocol emphasizes technical steps such as dissection of the embryological plane of the right mesocolon, high tie of ileocolic vessels, surgical trunk of Gillot dissection, and high tie of superior right colic vein (SRCV). In the second phase, a prospective observational study was conducted involving patients undergoing R-D3L surgery with this protocol between July 2015 and July 2021. Demographic, perioperative, and postoperative variables are analyzed, along with anatomopathological variables and oncological outcomes.A total of 33 patients were analyzed. Median operative time was 202 min. Perioperative bleeding occurred in 6%. Postoperative complications were mild (Clavien-Dindo III in 2%). Postoperative ileus was observed in 15%. No anastomotic dehiscence was reported. The median postoperative stay was 7 days. The median number of resected lymph nodes was 26, with 27% having positive nodes and 70% were classified as stage T3 or T4. After a median follow-up of 45 months, local recurrence, distant recurrence, and carcinomatosis rates were 0%. Mortality rate from other causes was 9%.The surgical protocol shown in the present study could help in the implementation of this technique in those units that consider it appropriate.© 2024. Springer Nature Switzerland AG.