直肠癌根治性切除术后局部复发很常见。手术切除被认为是局部复发直肠癌（LRRC）患者的主要治疗选择。 LRRC常常需要联合切除其他器官，尤其是后路复发的情况下，需要联合切除骶骨，使得手术具有很高的侵入性。静脉血栓栓塞（VTE）是术后致命的并发症之一，特别是在盆腔手术领域。我们没有发现关于 LRRC 手术术后 VTE 风险的报道，LRRC 是结直肠外科领域典型的高侵入性手术。本研究旨在评估LRRC患者手术中发生术后VTE的风险。2010年4月至2022年3月，我院共有166例患者接受了骨盆区域LRRC手术。回顾性比较临床病理背景和VTE发生率。在研究纳入的166例患者中，55例患者（33.1%）需要骶骨切除术。 121 例患者（73.3%）接受了预防 VTE 的药物预防，接受骶骨切除 LRRC 手术的患者 VTE 发生率为 9.09%（5/55 例患者），而接受骶骨切除术的患者 VTE 发生率为 1.8%（2/111 例）。患者）未进行骶骨切除术的患者。在单变量分析中，结合骶骨切除术被确定为 LRRC 手术中发生 VTE 的危险因素 (p = 0.047)。本研究表明，LRRC 手术结合骶骨切除术可能是 VTE 的重要危险因素。© 2024。作者。

Local recurrence is common after curative resections of rectal cancer. Surgical resection is considered a primary curative treatment option for patients with locally recurrent rectal cancer (LRRC). LRRC often requires a combined resection of other organs, especially in the case of posterior recurrence, which requires a combined resection of the sacrum, making the surgery highly invasive. Venous thromboembolism (VTE) is one of the lethal complications in the postoperative period, particularly in the field of pelvic surgery. We found no reports regarding the risks of postoperative VTE in surgery for LRRC, a typical highly invasive procedure in the field of colorectal surgery. This study aims to evaluate the risk of postoperative VTE in surgery for LRRC patients.From April 2010 to March 2022, a total of 166 patients underwent surgery for LRRC in the pelvic region at our institutions. Clinicopathological background and VTE incidence were compared retrospectively.Among the 166 patients included in the study, 55 patients (33.1%) needed sacral resection. Pharmacological prophylaxis for prevention of VTE was performed in 121 patients (73.3%), and the incidence of VTE was 9.09% (5/55 patients) among those who underwent surgery for LRRC with sacral resection, while it was 1.8% (2/111 patients) in those without sacral resection. In univariate analysis, the combination with sacral resection was identified as a risk factor for VTE in surgery for LRRC (p = 0.047).This study demonstrates that surgery for LRRC combined with sacral resection could be a significant risk factor for VTE.© 2024. The Author(s).