旨在调查癌症患者在唑仑膦酸治疗期间下颌骨密度的动态变化。该研究包括 14 名患者，每 28 天一次，每 28 天接受一次 4 mg 唑仑膦酸治疗骨转移。在所有 14 名患者中，随着时间的推移，对 CT 扫描上的下颌密度值进行测量。使用多元线性回归分析，开发了一个模型来预测唑仑膦酸注射次数“X1”对下颌密度“Y”动态的影响»。预测下颌骨密度的公式为 Y = 5.9 X1 49 HU。该模型由于研究设计而存在局限性，但肿瘤科医生和牙科医生仍然可以使用它来评估服用佐来膦酸的患者的下颌骨密度。

Was to investigate the dynamics of mandibular density in cancer patients during therapy with zolendronic acid.The study comprised 14 patients who received zolendronic acid at a dosage of 4 mg once every 28 days for bone metastases. In all 14 patients, measurements of mandibular density values on CT scans were performed over time.Using multiple linear regression analysis, a model was developed to predict the effect of the number of zolendronic acid injections «X1» on the dynamics of mandibular density «Y». The resulting formula for predicting mandibular density is Y = 5.9 X1 + 49 HU.The model has limitations due to the study design but still can be used by oncologists and dentists to assess mandibular density in patients taking zolendronic acid.