直到最近，慢性疼痛的治疗通常依赖于面对面的干预，尽管如今有更多的混合护理选择，但交付能力仍然面临挑战。专注于疼痛社会心理方面的数字项目可能会提供低门槛的替代方案。通过一项随机对照试验，我们调查了多模式移动应用程序的有效性。参与者（n = 198；82% 为女性，平均年龄 = 46.7 [13.1] 岁） ；平均疼痛持续时间为 13.6 [11.2] 年）的非恶性慢性疼痛被随机分为 6 周干预组 (n = 98) 或等待名单上的常规护理组 (n = 100)。干预措施包括定期使用用户引导的移动应用程序（Curable Inc.），该应用程序根据疼痛的生物心理社会模型提供信息，包括疼痛教育、冥想、认知行为治疗和表达性写作。共同主要结局是 6 周时的疼痛严重程度和干扰。与对照组相比，我们观察到干预组有显着改善，估计变化为 -0.67（95% 置信区间 [CI] -1.04 至 -0.29，P <.疼痛严重程度和干扰分别为 -0.01，d = 0.43）和 -0.60（95% CI -1.18 至 -0.03，P = .04，d = 0.27）。次要结果（患者报告结果测量信息系统疼痛干扰；疼痛灾难化；焦虑、抑郁；压力）有显着改善。应用程序使用频率与疼痛干扰改善 (P < .001) 和疼痛灾难化 (P = 0.018) 相关，并且干预组在 12 周时仍持续存在相对于基线的变化 (P < .05)。 短期移动应用程序与等待名单上的常规护理相比，干预导致身心健康结果显着改善。© 2024 作者。经泰勒许可出版

Until recently, treatments for chronic pain commonly relied on in-person interventions, and despite more hybrid care options today, capacity for delivery remains challenged. Digital programs focusing on the psychosocial aspects of pain may provide low-barrier alternatives.Through a randomized controlled trial, we investigated the effectiveness of a multimodal mobile application.Participants (n = 198; 82% women, mean age = 46.7 [13.1] years; mean pain duration 13.6 [11.2] years) with nonmalignant chronic pain were randomized to either a 6-week intervention (n = 98) or a wait-listed usual care group (n = 100). The intervention involved regular engagement with a user-guided mobile application (Curable Inc.) informed by the biopsychosocial model of pain that included pain education, meditation, cognitive behavioral therapy, and expressive writing. The co-primary outcomes were pain severity and interference at 6 weeks.We observed significant improvements in the intervention group compared to the control group with estimated changes of -0.67 (95% confidence interval [CI] -1.04 to -0.29, P < .001, d = 0.43) and -0.60 (95% CI -1.18 to -0.03, P = .04, d = 0.27) for pain severity and interference, respectively. There were significant improvements across secondary outcomes (Patient-Reported Outcome Measurement Information System pain interference; pain catastrophizing; anxiety, depression; stress). Frequency of app use was correlated with improved pain interference (P < .001) and pain catastrophizing (P = 0.018), and changes from baseline persisted in the intervention group at 12 weeks (P < .05).A short-term mobile app intervention resulted in significant improvements across physical and mental health outcomes compared to wait-listed usual care.© 2024 The Author(s). Published with license by Taylor & Francis Group, LLC.