本研究探索了一种使用提取的羧甲基纤维素（CMC）作为还原剂和稳定剂合成氧化钴纳米粒子（Co3O4NPs）的环保方法。通过各种分析表征的 Co3O4NPs 表现出尺寸范围为 10.9 至 28.2 nm 的晶体结构。显微成像证实其呈均匀的球形形态，平均直径为27.2nm。 Co3O4NPs 的生物活性得到了广泛的研究，突显了其比阿莫西林克拉维酸更优越的抗菌功效。这些纳米粒子表现出有效的抗氧化特性，并根据红细胞活力结果证明了潜在应用的安全性。此外，Co3O4NPs 对密歇根癌症基金会-7 (MCF-7) 乳腺癌细胞表现出显着的效力，并显示出有前景的 α-淀粉酶抑制活性，突出了它们作为抗氧化、抗菌、抗癌和 α-淀粉酶抑制测定的多功能治疗潜力。版权© 2024。由 Elsevier B.V. 出版

This study explores an eco-friendly method for synthesizing Cobalt oxide nanoparticles (Co3O4NPs) using extracted carboxymethyl cellulose (CMC) as a reducing and stabilizing agent. The Co3O4NPs, characterized via various analyses, demonstrated a crystalline structure with sizes ranging from 10.9 to 28.2 nm. Microscopic imaging confirmed a uniform spherical morphology with an average diameter of 27.2 nm. The biological activities of Co3O4NPs were investigated extensively, highlighting their superior antibacterial efficacy compared to amoxicillin-clavulanic acid. These nanoparticles exhibited potent antioxidant properties and demonstrated safety for potential applications based on erythrocyte viability results. Additionally, Co3O4NPs displayed significant potency against Michigan Cancer Foundation-7 (MCF-7) breast cancer cells and showed promising α-amylase enzyme inhibitory activity, highlighting their multifunctional therapeutic potential as antioxidant, antibacterial, anticancer, and alpha-amylase inhibition assay.Copyright © 2024. Published by Elsevier B.V.