磷酸盐间质肿瘤（PMT）是一种罕见的肿瘤，会导致骨并发症和肌病。在组织学上，PMT 显示出梭形细胞、破骨细胞样巨细胞、嗜碱性基质和絮状或“脏”钙化的混合。在这里，我们描述了一例右髋和股骨近端 PMT 病例，最初怀疑是多发性骨髓瘤，表现为溶骨性病变和碱性磷酸酶升高。恶性肿瘤检测呈阴性，但随后的活检证实了 PMT。该患者接受了髋部活检、股骨切除和半关节置换术，并建议进行 MRI 随访。© 2024 作者。由爱思唯尔公司代表华盛顿大学出版。

Phosphaturic mesenchymal tumor (PMT) is a rare tumor causing bone complications and myopathy. Histologically, PMT displays a mix of spindled cells, osteoclast-like giant cells, basophilic matrix, and flocculent or "grungy" calcification. Here we describe a case of PMT in the right hip and proximal femur, initially suspected to be multiple myeloma, presenting with osteolytic lesions and elevated alkaline phosphatase. Tests for malignancy were negative, but a subsequent biopsy confirmed PMT. The patient underwent hip biopsy, femur resection, and hemiarthroplasty, with follow-up MRI recommended.© 2024 The Authors. Published by Elsevier Inc. on behalf of University of Washington.