宫颈癌患者术后化疗后会出现焦虑、抑郁、癌因性疲劳等症状，导致生活质量下降，给患者的康复带来挑战。因此，有必要探索有效的护理方法。本研究旨在探讨基于网络的积极心理护理模式对宫颈癌术后化疗患者负性情绪、癌因性疲劳、自我管理效能、治疗依从性及生活质量的影响。纳入 2019 年 1 月至 2023 年 12 月期间在我院接受手术干预的 101 例宫颈癌患者。其中接受常规护理模式的患者为对照组（n = 48），而接受网络积极心理护理的患者为对照组（n = 48）。模式被纳入研究组（n = 53）。对所有研究对象进行各种评估指标，包括基线特征、治疗依从性、汉密尔顿焦虑量表（HAMA）、汉密尔顿抑郁量表（HAMD）、修订派珀疲劳量表（RPFS）、中文版研究策略患者促进健康 (C-SUPPH) 和欧洲癌症研究与治疗组织生活质量调查问卷 -Core 30 (EORTC QLQ-C30)。另外，比较两组的焦虑/抑郁、癌因性疲劳、自我管理效果、治疗依从性、生活质量。干预后，两组的HAMA评分、HAMD评分、RPFS评分均显着下降。与干预前相比（p < 0.05）。然而，C-SUPPH 评分比干预前显着增加（p < 0.05）。我们观察到干预后研究组的 HAMA、HAMD 和 RPFS 评分显着低于对照组（p < 0.05）。相比之下，C-SUPPH 评分显着较高 (p < 0.05)。干预后，研究组的治疗依从性明显优于对照组。此外，EORTC QLQ-C30评分显着高于对照组（p < 0.05）。基于网络的积极心理护理模式可以有效缓解宫颈癌术后患者的负性情绪和癌因性疲劳。手术化疗，从而提高他们的生活质量。此外，该模型还提高了患者的自我管理有效性和治疗依从性。这些发现为宫颈癌患者术后化疗的护理提供了新的见解，强调了其临床意义。

Cervical cancer patients with post-operative chemotherapy experience anxiety, depression, and cancer-related fatigue, leading to a decline in their quality of life and posing challenges to the rehabilitation of patients. Therefore, it is necessary to explore effective nursing methods. This study aimed to investigate the effects of a web-based positive psychological nursing model on negative emotions, cancer-related fatigue, self-management efficacy, treatment compliance, and quality of life among cervical cancer patients with post-operative chemotherapy.This retrospective study included 101 cervical cancer patients who underwent surgical intervention at our hospital between January 2019 and December 2023. Patients who received the usual mode of care were included in the control group (n = 48), while those who received the web-based positive psychological care mode were included in the study group (n = 53). For all study subjects, various assessment indices were evaluated, including baseline characteristics, treatment adherence, and the Hamilton Anxiety Scale (HAMA), Hamilton Depression Scale (HAMD), Revised Piper Fatigue Scale (RPFS), the Chinese version of the Strategies Used by Patients to Promote Health (C-SUPPH), and European Organization for Research and Treatment of Cancer Quality of Life questionnaire -Core 30 (EORTC QLQ-C30). Additionally, anxiety/depression, cancer-related fatigue, self-management efficacy, treatment compliance, and quality of life were compared between the two groups.After the intervention, the HAMA score, HAMD score, and RPFS score were significantly decreased for both groups compared to before intervention (p < 0.05). However, the C-SUPPH score was significantly increased than before intervention (p < 0.05). We observed that HAMA, HAMD, and RPFS scores were substantially lower in the study group than those in the control group after intervention (p < 0.05). In contrast, C-SUPPH scores were significantly higher (p < 0.05). After the intervention, treatment compliance was significantly better in the study group compared to the control group. Furthermore, the EORTC QLQ-C30 score was substantially higher than that of the control group (p < 0.05).The network-based positive psychological nursing model can effectively alleviate negative emotions and cancer-related fatigue in cervical cancer patients who have undergone post-operative chemotherapy, thereby improving their quality of life. Additionally, this model improves patients' self-management effectiveness and treatment compliance. These findings provide novel insights into the nursing of cervical cancer patients with post-operative chemotherapy, underscoring its clinical significance.