必要性是卵巢组织冷冻保存之母：我们能兑现承诺吗？
Necessity is the Mother of Ovarian Tissue Cryopreservation: Can We Live Up to the Promise?
发表日期：2024 Aug 24
作者：
Nanette Santoro
来源：
FERTILITY AND STERILITY
摘要：
推动卵巢组织冷冻保存领域发展的技术必要性源于挽救面临性腺毒性治疗的癌症儿童的生殖潜力的紧迫性。该领域迅速扩展，许多中心都提供这项服务，但由于组织冷冻和利用之间存在时间差，因此几乎没有报告结果。关于患者选择的最佳实践、冷冻和解冻的最佳技术以及伴随冷冻和解冻过程的卵母细胞大量损失的问题仍然存在。在这一重要的临床进展可以说完全兑现其承诺之前，需要解决这些问题。版权所有 © 2024。由 Elsevier Inc. 出版。
The technological necessity that has driven the field of ovarian tissue cryopreservation arose from the urgency of saving the reproductive potential of children with cancer facing gonadotoxic therapies. The field has expanded rapidly, with many centers offering this service, yet there are few outcomes reported because of the time lag between tissue freezing and its utilization. Questions about the best practices for patient selection, the best techniques for freezing and thawing, and the large loss of oocytes that accompanies the freezing and thawing process remain. These problems will need to be solved before this important clinical advance can be said to fully live up to its promise.Copyright © 2024. Published by Elsevier Inc.