社区绿化可能通过促进身体活动和社会融合、减少压力和接触空气污染、噪音和极端温度来有益于前列腺癌的长期生存。我们在健康专业人员随访研究中研究了社区绿化与前列腺癌幸存者长期身体和心理社会生活质量之间的关系。我们纳入了 2008 年至 2016 年间美国各地被诊断患有非转移性前列腺癌的 1,437 名个体。使用基于 Landsat 卫星图像的归一化植被指数 (NDVI) 测量每个人的邮寄地址 1230m 缓冲区内的邻里绿化度。我们拟合广义线性混合效应模型来评估绿色度（以五分位数为单位）与纵向患者报告的前列腺癌特定身体和社会心理生活质量结果测量的关联，并根据时变的个人和社区水平的人口因素和临床因素进行调整.最大的症状负担是在性方面。超过一半的幸存者在诊断时报告记忆功能良好且没有抑郁症状。在完全调整的模型中，自诊断以来的累积平均绿度与较少的活力/激素症状相关（最高五分位数，Q5，与最低五分位数，Q1：平均差：-0.46，95％置信区间[CI]：-0.81，-0.12） 。身体生活质量的其他领域，包括肠道症状、尿失禁、尿路刺激和性症状，总体上并没有因绿色而存在差异。总体而言，心理社会生活质量并没有因绿色程度而存在差异（Q5 与 Q1，比值比 [95% CI]：记忆功能：1.01 [0.61，1.73]；缺乏抑郁迹象：1.10 [0.63，1.95]；幸福感：1.17 [ 0.71, 1.91])。在前列腺癌长期存活期间，自诊断以来累计平均 1230m 的绿色与较少的活力/荷尔蒙症状相关。总体而言，身体生活质量和社会心理生活质量的其他领域并没有因绿色程度而有所不同。局限性包括潜在的非差异曝光测量误差和 NDVI 缺乏时间活动模式。版权所有 © 2024。由 Elsevier Inc. 发布。

Neighborhood greenness may benefit long-term prostate cancer survivorship by promoting physical activity and social integration, and reducing stress and exposure to air pollution, noise, and extreme temperatures. We examined associations of neighborhood greenness and long-term physical and psychosocial quality of life in prostate cancer survivors in the Health Professionals Follow-up Study.We included 1,437 individuals diagnosed with non-metastatic prostate cancer between 2008 and 2016 across the United States. Neighborhood greenness within a 1230m buffer of each individual's mailing address was measured using the Landsat satellite image-based Normalized Difference Vegetation Index (NDVI). We fit generalized linear mixed effect models to assess associations of greenness (in quintiles) with longitudinal patient reported outcome measures on prostate cancer-specific physical and psychosocial quality of life, adjusting for time-varying individual- and neighborhood-level demographic factors and clinical factors.The greatest symptom burden was in the sexual domain. More than half of survivors reported good memory function and the lack of depressive signs at diagnosis. In fully adjusted models, cumulative average greenness since diagnosis was associated with fewer vitality/hormonal symptoms (highest quintile, Q5, vs lowest quintile, Q1: mean difference: -0.46, 95% confidence interval [CI]: -0.81, -0.12). Other domains of physical quality of life, including bowel symptoms, urinary incontinence, urinary irritation, and sexual symptoms, did not differ by greenness overall. Psychosocial quality of life did not differ by greenness overall (Q5 vs Q1, odds ratio [95% CI]: memory function: 1.01 [0.61, 1.73]; lack of depressive signs: 1.10 [0.63, 1.95]; and wellbeing: 1.17 [0.71, 1.91]).During long-term prostate cancer survivorship, cumulative average 1230m greenness since diagnosis was associated with fewer vitality/hormonal symptoms. Other domains of physical quality of life and psychosocial quality of life did not differ by greenness overall. Limitations included potential non-differential exposure measurement error and NDVI's lack of time-activity pattern.Copyright © 2024. Published by Elsevier Inc.