姜黄素是从姜黄中提取的天然多酚类化合物，具有抗菌、抗氧化、抗肿瘤、预防和治疗神经系统疾病等多种生物活性，广泛应用于食品和医药领域。然而姜黄素水溶性差、稳定性差等缺点限制了姜黄素的实际应用。为了克服这些缺陷并增强其功能特性，各种纳米系统（脂质体、聚合物纳米颗粒、蛋白质纳米颗粒、固体脂质纳米颗粒、金属纳米颗粒等）已被广泛用于姜黄素的封装和递送。尽管姜黄素纳米制剂发展迅速，但仍缺乏对其制备和性能的全面综述。本文综述了姜黄素纳米载体的构建、作用机制、纳米载体的制备方法以及姜黄素纳米载体在食品和医药领域的应用，为姜黄素纳米载体的高效生物利用、产品化提供理论基础和技术支撑。姜黄素的开发和早期临床应用。© 2024 IOP Publishing Ltd。保留所有权利，包括文本和数据挖掘、人工智能培训和类似技术。

Curcumin is a natural polyphenolic compound extracted from turmeric with antibacterial, antioxidant, antitumor, preventive and therapeutic neurological disorders and a variety of bioactivities, which is widely used in the field of food and medicine. However, the drawbacks of curcumin such as poor aqueous solubility and stability have limited the practical application of curcumin. To overcome these defects and enhance its functional properties, various nanoscale systems (liposomes, polymer nanoparticles, protein nanoparticles, solid lipid nanoparticles, metal nanoparticles, etc) have been extensively employed for curcumin encapsulation and delivery. Despite the rapid development of curcumin nanoformulations, there is a lack of comprehensive reviews on their preparation and properties. This review provides an overview of the construction of curcumin nano-delivery systems, mechanisms of action, nanocarrier preparation methods and the applications of curcumin nanocarriers in the food and pharmaceutical fields to provide a theoretical basis and technological support for the efficient bio-utilization, product development and early clinical application of curcumin.© 2024 IOP Publishing Ltd. All rights, including for text and data mining, AI training, and similar technologies, are reserved.