结直肠癌和胰腺癌是最常见的胃肠道癌症。其手术治疗的发病率很高：25% 至 30% 的病例会出现并发症，通常会延长恢复时间并延迟辅助治疗的开始，进而导致更糟糕的肿瘤结果。多模式围手术期管理 (mPOM) 的目标是通过围手术期措施的组合来降低术后并发症发生率。本胃肠道肿瘤围手术期管理指南 (POMGAT) 满足科学协会规定的 S3 指南的所有要求德国医学会（Arbeitsgemeinschaft der Wissenschaftlichen Medizinischen Fachgesellschaften，AWMF）。其中包括系统的文献检索、所含出版物的质量评估、根据 GRADE 方法评估证据的可靠性以及结构化的共识过程。荟萃分析表明，mPOM 降低了胰腺和结直肠癌的并发症发生率切除（分别为 RD 0.96，95% 置信区间 [0.92；0.99] 和 RR 0.66 [0.54；0.80]）。这将胰腺切除术后的住院时间平均缩短了 2.33 天 [-2.98； -1.69] 结直肠切除术后平均 2.59 天 [-3.22；-1.69] -1.97]。遵守胰腺癌和结直肠癌手术的 POMGAT-S3 指南与改善康复相关，这可以导致更快地恢复预期肿瘤治疗 (RIOT)，从而获得更好的长期结果。这些建议不仅限于胃肠道癌症手术；它们还可以应用于良性疾病的内脏手术以及妇科和泌尿科手术。

Colorectal and pancreatic carcinoma are the most common cancers of the gastrointestinal tract. Their surgical treatment carries a high morbidity: Complications arise in 25% to 30% of cases, often prolonging recovery times and delaying the initiation of adjuvant therapy, leading, in turn, to worse oncological outcomes. The goal of multimodal perioperative management (mPOM) is to lower the postoperative complication rate through a combination of perioperative measures.This guideline on the perioperative management of gastrointestinal tumors (POMGAT) meets all requirements for an S3 guideline as specified by the Association of the Scientific Medical Societies in Germany (Arbeitsgemeinschaft der Wissenschaftlichen Medizinischen Fachgesellschaften, AWMF). These include a systematic literature search, quality assessment of the included publications, an evaluation of the reliability of the evidence according to the GRADE approach, and a structured consensus process.Meta-analyses have shown that mPOM lowers the complication rates of both pancreatic and colorectal resections (RD 0.96 with 95% confidence interval [0.92; 0.99] and RR 0.66 [0.54; 0.80], respectively). This shortens the hospital stay after pancreatic resections by a median of 2.33 days [-2.98; -1.69] and after colorectal resections by a median of 2.59 days [-3.22; -1.97].Adherence to the POMGAT-S3 guideline for pancreatic and colorectal cancer surgery is associated with improved recovery, which can lead to a faster return to intended oncological treatment (RIOT) and thus to better long-term outcomes. These recommendations are not restricted to gastrointestinal cancer surgery; they can also be applied to visceral surgery for benign conditions, as well as to gynecological and urological operations.