用于癌症检测的水凝胶生物传感器的最新进展。
Recent Advances in Hydrogel-Based Biosensors for Cancer Detection.
发表日期：2024 Aug 27
作者：
Shengwei Sun, Jinju Chen
来源：
BIOSENSORS & BIOELECTRONICS
摘要：
早期癌症检测对于有效治疗至关重要，但目前的方法存在局限性。新型生物材料，例如水凝胶，为开发用于癌症检测的生物传感器提供了有前途的替代方案。水凝胶是亲水聚合物的三维交联网络，具有与生物组织相似的特性。它们可以与各种生物传感器结合，以实现高灵敏度、特异性和稳定性。本综述总结了用于癌症检测的基于水凝胶的生物传感器的最新进展、其合成、应用和挑战。它还讨论了这个新兴领域的影响和未来方向。
Early cancer detection is crucial for effective treatment, but current methods have limitations. Novel biomaterials, such as hydrogels, offer promising alternatives for developing biosensors for cancer detection. Hydrogels are three-dimensional and cross-linked networks of hydrophilic polymers that have properties similar to biological tissues. They can be combined with various biosensors to achieve high sensitivity, specificity, and stability. This review summarizes the recent advances in hydrogel-based biosensors for cancer detection, their synthesis, their applications, and their challenges. It also discusses the implications and future directions of this emerging field.