基因检测提高了脑肿瘤诊断的准确性，现在可以根据脑肿瘤的类型制定治疗方案。相比之下，影响康复后日常生活活动（ADL）独立性改善的因素尚未明确，特别是肿瘤类型的作用。在这项 358 名参与者的回顾性队列研究中，我们分析了一家急症护理医院提供的功能独立测量 (FIM) 从康复前到康复后的变化。使用多元回归来确定 FIM 增益是否与年龄、性别、入院前卡诺夫斯基体能状态 (KPS)、康复天数、平均每日治疗持续时间（分钟/天）以及肿瘤复发和类型（WHO 1 级， 2、3和4神经胶质瘤；原发性中枢神经系统淋巴瘤；和转移性脑肿瘤）。结果显示，年龄较大（β -0.183）、肿瘤复发（β -0.137）、入院前KPS < 80（β -0.180）和较高的基线总FIM评分（β -0.470）与较低的FIM增益相关，而平均每日治疗持续时间（β 0.153）与较高的 FIM 增益相关。脑肿瘤类型与 FIM 增益无关。与脑肿瘤类型差异相比，ADL 独立性的提高更多地受到人口统计学、功能状态和治疗因素的影响。版权所有 © 2024 Wolters Kluwer Health, Inc. 保留所有权利。

Genetic testing has improved the accuracy of diagnosis of brain tumors, and treatment is now tailored to the type of brain tumor. In contrast, the factors that influence the improvement in independence in activities of daily living (ADLs) following rehabilitation have not been clarified, particularly the role of tumor type. In this retrospective cohort study of 358 participants, we analyzed changes in the Functional Independence Measure (FIM) from pre-rehabilitation to post-rehabilitation provided in an acute care hospital. Multiple regression was used to determine whether FIM gain is associated with age, gender, preadmission Karnofsky Performance Status (KPS), number of rehabilitation days, average duration of daily therapy (min/day), and tumor recurrence and type (WHO grade 1, 2, 3, and 4 gliomas; primary central nervous system lymphomas; and metastatic brain tumors). The results showed that older age (β -0.183), tumor recurrence (β -0.137), preadmission KPS < 80 (β -0.180), and higher baseline total FIM score (β -0.470) were associated with lower FIM gain whereas the average duration of daily therapy (β 0.153) was associated with higher FIM gain. Brain tumor type was not associated with FIM gain. Improved independence in ADLs is more influenced by demographic, functional status, and treatment factors than differences in brain tumor type.Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.