宫颈癌主要由 HPV 引起，在莫桑比克等国家很流行，艾滋病毒感染者的风险较高。醋酸目视检查 (VIA) 筛查方法可能会受到沙眼衣原体 (CT) 和淋病奈瑟菌 (NG) 等性传播感染的影响。本研究利用莫桑比克 DREAM 计划中的 VIA 检查 HIV 阳性和阴性女性的 CT 和 NG 患病率。在这项横断面研究中，于 2021 年 7 月 1 日至 2022 年 5 月 31 日在马普托的 DREAM 计划设施进行，宫颈标本取自 VIA 阳性患者。使用 Cobas® 4800 DNA CT/NG 测试进行 CT/NG 测试。统计分析侧重于关联性和患病率，考虑人口、临床和暴露数据。在 117 名女性中，我们观察到 CT 患病率为 6.8% (8/117)，NG 患病率为 2.6% (3/117)。未观察到 CT/NG 感染率与年龄、HIV 状况、VIA 结果或高危 HPV (hrHPV) 等因素之间存在显着关联。我们发现患有宫颈病变的参与者中 hrHPV 感染率为 47%；没有观察到 hrHPV 与 CT/NG 感染之间存在显着关联。这项研究强调了莫桑比克 VIA 阳性女性中 CT 和 NG 的患病率，强调了 STI 负担，并建议将 STI 筛查纳入宫颈癌预防策略。

Cervical cancer, primarily from HPV, is prevalent in countries like Mozambique, with HIV individuals at higher risk. The Visual Inspection with Acetic Acid (VIA) screening method can be influenced by STIs like Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG). This study examines CT and NG prevalence in HIV-positive and negative women using VIA in Mozambique's DREAM program.In this cross-sectional research conducted at a DREAM program facility in Maputo from 01/07/2021 to 31/05/2022, cervical specimens were taken from VIA-positive patients. CT/NG testing was performed using the Cobas® 4800 DNA CT/NG test. Statistical analyses focused on associations and prevalence rates, considering demographic, clinical, and exposure data.Among 117 women, we observed a CT prevalence of 6.8% (8/117) and an NG prevalence of 2.6%(3/117). No significant associations between CT/NG infection rates and factors such as age, HIV status, VIA results, or high-risk HPV (hrHPV) was observed. We found a 47% prevalence of hrHPV infections among participants with cervical lesions; no significant association between hrHPV and CT/NG infections was observed.This study highlights the prevalence of CT and NG in VIA-positive women in Mozambique, emphasizing the STI burden and suggesting integration of STI screening in cervical cancer prevention strategies.