本研究旨在总结肺癌患者疲劳-疼痛-睡眠障碍症状群的非药物干预最有效的证据，为临床团队和肺癌患者提供循证管理方法。以“6S”金字塔模型为指导我们从相关网站和数据库中检索了有关疲劳、疼痛和睡眠障碍管理的证据，并检索了未发表的灰色文献。检索时间范围为建库至2023年9月30日。两名研究者独立评估文献质量，采用Appraisal ofGuidelines for Research andEvaluation II（AGREE II）为指南，以及Assessment of Multiple Systematic Reviews II（AMSTAR） II) 系统评价。两人按照高质量证据第一原则和新发表的证据独立提取和总结证据。纳入的证据由 JBI 证据预分级系统进行分级。共检索到 52,238 篇文章，其中 60 篇文章，包括 18 篇指南、18 篇 JBI 最佳实践建议、一篇 Up To Date 临床实践和 23 篇系统评价包括。总体而言，总结了筛选、评估、管理、教育、转诊和随访六个维度的 49 条证据。 43 个证据为 1 级，3 个证据为 4 级，3 个证据为 5 级。非药物干预对肺癌患者疲劳-疼痛-睡眠障碍症状群的最佳 49 个证据本研究对这些非药物干预措施进行了总结，这些非药物干预措施科学、全面。本研究可为临床团队改进疲劳-疼痛-睡眠障碍症状群管理提供指导。这些证据项目可以由临床团队实施，以减轻肺癌患者的症状负担并提高症状的自我管理能力。版权所有 © 2024 Elsevier Inc. 保留所有权利。

This study aimed to summarize the most effective evidence on nonpharmacological interventions for the fatigue-pain-sleep disturbance symptom cluster in lung cancer patients and to provide evidence-based management methods for clinical team and lung cancer patients.Guided by the "6S" pyramid model, we retrieved evidence on fatigue, pain, and sleep disturbance management from relevant websites and databases, and unpublished gray literature was also searched. The time frame of the search ranged from database establishment to September 30, 2023. Two researchers independently evaluated the literature quality using the Appraisal of Guidelines for Research and Evaluation II (AGREE II) for guidelines, and the Assessment of Multiple Systematic Reviews II (AMSTAR II) for systematic reviews. Two people independently extracted and summarized the evidence according to the first principle of high-quality evidence and newly published evidence. The included evidence was graded by the JBI Evidence Pre-Grading System.A total of 52,238 articles were retrieved, of which 60 articles, including 18 guidelines, 18 JBI best practice recommendations, one Up To Date clinical practice, and 23 systematic reviews, were included. Overall, 49 pieces of evidence from six dimensions-screening, assessment, management, education, referral, and follow-up-were summarized. Forty-three pieces of evidence were level 1, three pieces of evidence were level 4, and three pieces of evidence were level 5.The best 49 pieces of evidence on nonpharmacological interventions for the fatigue-pain-sleep disturbance symptom cluster in lung cancer patients were summarized in this study, and these nonpharmacological interventions are scientific and comprehensive.This study can provide guidance for clinical team to improve the fatigue-pain-sleep disturbance symptom cluster management. These evidence items can be implemented by clinical team to reduce the symptom burden and improve the self-management ability of symptoms in lung cancer patients.Copyright © 2024 Elsevier Inc. All rights reserved.