使用 18F-FAPI-04 PET/CT 检测一例甲状旁腺癌的肌肉转移。
Detection of Muscular Metastasis in a Case of Parathyroid Carcinoma Using 18F-FAPI-04 PET/CT.
发表日期：2024 Aug 28
作者：
Jie Chen, Min Zhao, Qi An, Lan Wei, Bin Chen
来源：
CLINICAL NUCLEAR MEDICINE
摘要：
一名 46 岁女性，两年前因甲状旁腺癌接受手术。在随访期间，患者出现甲状旁腺激素升高（127.50 pg/mL；正常，15-65）。在 18F-FDG 和 11C-胆碱 PET/CT 成像中未观察到 18F-FDG 或 11C-胆碱的异常摄取。该患者参加了 18F-FAPI PET/CT 成像临床试验，结果显示左侧胸锁乳突肌内存在强烈局灶性摄取的病变。患者接受了手术。术后病理学和免疫组织化学分析证实甲状旁腺癌转移。版权所有 © 2024 Wolters Kluwer Health, Inc. 保留所有权利。
A 46-year-old woman underwent surgery for parathyroid carcinoma 2 years ago. During follow-up, the patient presented with elevated parathyroid hormone (127.50 pg/mL; normal, 15-65). No abnormal uptake of 18F-FDG or 11C-choline was observed on 18F-FDG and 11C-choline PET/CT imaging. The patient was enrolled in a clinical trial for 18F-FAPI PET/CT imaging, revealing a lesion with intense focal uptake within the left sternocleidomastoid muscle. The patient underwent surgery. Postoperative pathology and immunohistochemical analysis confirmed parathyroid carcinoma metastasis.Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.