海藻，包括大型藻类和微藻类，已成为具有有效抗癌特性的生物活性化合物的有前途且丰富的来源。尽管它们具有显着的治疗潜力，但这些肽的临床应用受到生物利用度差和对酶降解的敏感性等挑战的阻碍。为了克服这些限制，人们探索了创新的递送系统，特别是纳米载体。纳米载体，包括脂质体、纳米颗粒和胶束，在增强海洋藻肽的稳定性、溶解度和生物利用度、确保控释和延长治疗效果方面表现出显着的功效。封装在纳米载体中的海洋藻肽可显着提高生物利用度，确保更有效地在体内吸收和利用。临床前研究显示出有希望的结果，表明基于纳米载体的递送系统可以显着改善海洋藻肽的药代动力学特征和治疗结果。这篇综述深入研究了海洋藻肽的多种抗癌机制，包括诱导细胞凋亡、破坏细胞周期进程和抑制血管生成。进一步的研究重点是优化纳米载体配方、进行全面的临床试验以及对海洋藻肽的持续探索，这为开发创新、有效和可持续的癌症疗法带来了巨大希望。

Marine algae, encompassing both macroalgae and microalgae, have emerged as a promising and prolific source of bioactive compounds with potent anticancer properties. Despite their significant therapeutic potential, the clinical application of these peptides is hindered by challenges such as poor bioavailability and susceptibility to enzymatic degradation. To overcome these limitations, innovative delivery systems, particularly nanocarriers, have been explored. Nanocarriers, including liposomes, nanoparticles, and micelles, have demonstrated remarkable efficacy in enhancing the stability, solubility, and bioavailability of marine algal peptides, ensuring controlled release and prolonged therapeutic effects. Marine algal peptides encapsulated in nanocarriers significantly enhance bioavailability, ensuring more efficient absorption and utilization in the body. Preclinical studies have shown promising results, indicating that nanocarrier-based delivery systems can significantly improve the pharmacokinetic profiles and therapeutic outcomes of marine algal peptides. This review delves into the diverse anticancer mechanisms of marine algal peptides, which include inducing apoptosis, disrupting cell cycle progression, and inhibiting angiogenesis. Further research focused on optimizing nanocarrier formulations, conducting comprehensive clinical trials, and continued exploration of marine algal peptides holds great promise for developing innovative, effective, and sustainable cancer therapies.