由于潜在的炎症、免疫抑制和营养不良，克罗恩病 (CD) 的手术被认为会产生更多并发症。 我们试图利用标准化围手术期方案，在大容量三级中心研究 CD 患者和癌症患者的右侧结肠切除术的结果。这是一项针对所有 CD 患者或接受回结肠切除术的患者结果的回顾性研究或从 2013 年至 2022 年在同一机构进行右半结肠切除术和回结肠吻合术。如果患者同时接受其他手术或造口术，则被排除在外。使用 Wilcoxon 秩和和卡方检验进行单变量分析，使用逻辑回归和线性回归进行多变量分析。总共纳入了 141 名 CD 患者和 589 名癌症患者。患有克罗恩病的患者明显更年轻，体重指数较低，患糖尿病和高血压等合并症的可能性也较小。患有 CD 的患者不太可能有吸烟史或既往接受过腹部手术，但更有可能服用类固醇。两组的腹腔镜检查、术中并发症和失血率相似。尽管术前和术中存在差异，但 CD 患者和癌症患者的住院时间 (LOS)、再入院、再次手术和死亡率相似。 两组之间的手术结果均无显着差异。 在多变量分析中，在控制其他特征的情况下，CD 诊断与再次手术、再入院、死亡率或 LOS 无关。通过使用标准化围手术期方案，在具有 CD 专业知识的大容量中心进行 CD 手术的成本可与癌症等其他适应症的结果。© 2024。Springer Nature Switzerland AG。

Surgery for Crohn's disease (CD) is considered to have more complications due to the underlying inflammation, immunosuppression, and malnutrition. We sought to study the outcomes of right-sided colonic resection in patients with CD and patients with cancer at a high-volume tertiary center utilizing a standardized perioperative protocol.This is a retrospective study of outcomes for all patients with CD or patients undergoing ileocolic resection or right hemicolectomy with ileocolic anastomosis at a single institution from 2013 to 2022. Patients were excluded if they simultaneously underwent another procedure or ostomy creation. Data were analyzed using Wilcoxon rank-sum and chi-squared tests for univariate analyses, and logistic and linear regressions for multivariate analyses.In total 141 patients with CD and 589 patients with cancer were included. Patients with CD were significantly younger with lower body mass index and less likely to have comorbidities, including diabetes and hypertension. Patients with CD were less likely to have a smoking history or prior abdominal surgery, but more likely to be on steroids. Both groups had similar rates of laparoscopy, intraoperative complications, and blood loss. Despite the preoperative and intraoperative differences, both patients with CD and patients with cancer had similar lengths of stay (LOS), readmission, reoperation, and mortality rates. None of the surgical outcomes differed significantly between the two groups. On multivariate analysis, CD diagnosis was not associated with reoperation, readmission, mortality, or LOS while controlling for other characteristics.With the use of standardized perioperative protocols, surgery for CD at a high-volume center with expertise in CD can be performed with comparable results to other indications like cancer.© 2024. Springer Nature Switzerland AG.