迁移体是最近发现的细胞器，形成于迁移细胞后面的回缩纤维 (RF) 的末端或叉处，并通过细胞迁移从细胞中排出。迁移小体含有信号分子，这些信号分子与迁移小体一起被周围细胞捕获或在迁移小体破裂后释放到细胞外环境中。最后，通过这些信号分子的作用，迁移体促进整个信息传递过程。此外，迁移体还充当“清道夫”，通过清除细胞中受损的线粒体来确保细胞活力。因此，迁移小体在时间、空间、特定化学信息的整合和细胞有害物质的清除中发挥着关键作用，这对于掌握迁移小体的功能至关重要。本文深入探讨了迁移小体研究的最新进展，涵盖迁移小体的发现、分布、结构和特征、发生和调控机制及其与疾病的相关性等方面。此外，我们仔细审查了癌症领域内迁移体的现有研究结果，研究了它们对癌症的潜在影响和前瞻性研究途径。版权所有 © 2024 Tang, Huang, Wang, Luan, Deng, Xu, Fan, He, Zhou, Wang, Li 、曾、李、周。

Migrasomes are recently identified organelles that form at the ends or forks of retraction fibers (RFs) behind migrating cells and are expelled from the cell through cell migration. Migrasomes contain signaling molecules which are captured by surrounding cells along with migrasomes or released into the extracellular environment following the rupture of the migrasomes. Finally, through the action of these signaling molecules, migrasomes facilitate the entire process of information conveyance. In addition, migrasomes also serves as a "scavenger" by removing damaged mitochondria from the cell to ensure cellular viability. Thus, migrasomes play a pivotal role in the integration of temporal, spatial, specific chemical information and the clearance of cellular harmful substances, critical for grasping migrasomes' functions. This review delves into the latest advancements in migrasomes research, covering aspects such as migrasomes' discovery, distribution, structure and characteristics, genesis and regulation mechanisms, and their correlation with diseases. Additionally, we scrutinize the present investigational findings on migrasomes within the cancer domain, examining their potential impact on cancer and prospective research avenues.Copyright © 2024 Tang, Huang, Wang, Luan, Deng, Xu, Fan, He, Zhou, Wang, Li, Zeng, Li and Zhou.