与居住在没有持续贫困的社区的个体相比，居住在社会经济弱势社区的乳腺癌患者往往面临更差的结果（例如死亡率）。为了检查持续的社区贫困和乳腺肿瘤特征、手术治疗和死亡率。对女性的回顾性队列分析研究对象为2010年1月1日至2018年12月31日期间诊断为I至III期乳腺癌的18岁或以上，并随访至2020年12月31日。数据来自监测、流行病学和最终结果计划，并对 2023 年 8 月至 2024 年 3 月进行了数据分析。居住在受持续贫困影响的地区的定义是 20% 或以上的人口生活水平低于标准。贫困水平持续约 30 年。全因死亡率和乳腺癌特异性死亡率。在 312145 名患者（平均 [SD] 年龄，61.9 [13.3] 岁）中，20007 年 (6.4%) 生活在持续贫困的 CT 中。与生活在没有持续贫困地区的个人相比，居住在持续贫困地区的患者更有可能被认为是黑人（20007 年中的 8735 名 [43.7%] 对比 292138 名中的 29588 名 [10.1%]；P < .001）或西班牙裔（20007 年中的 2605 例 [13.0%] 对比 292138 例中的 23792 例 [8.1%]；P< .001），并且具有更具侵袭性的肿瘤特征，包括更高级别的疾病、三阴性乳腺癌和晚期。居住在持续贫困地区的患者接受乳房切除术和腋窝淋巴结清扫术的比例较高。生活在持续贫困的 CT 地区与乳腺癌特异性（调整后风险比 [AHR]，1.10；95% CI，1.03-1.17）和全因乳腺癌（AHR，1.13；95% CI，1.08-）风险较高相关。 1.18）死亡率。早在诊断后 3 年，乳腺癌特异性死亡风险（比率 [RR]，1.80；95% CI，1.68-1.92）和全因死亡风险（RR，1.62；95% CI，1.56-1.70）就出现了差异。在这项队列研究中，对象是 2010 年至 2018 年间被诊断患有 I 至 III 期乳腺癌的 18 岁或以上女性，生活在持续贫困的社区对肿瘤特征、手术治疗和死亡率有影响。

Patients with breast cancer residing in socioeconomically disadvantaged communities often face poorer outcomes (eg, mortality) compared with individuals living in neighborhoods without persistent poverty.To examine persistent neighborhood poverty and breast tumor characteristics, surgical treatment, and mortality.A retrospective cohort analysis of women aged 18 years or older diagnosed with stage I to III breast cancer between January 1, 2010, and December 31, 2018, and followed up until December 31, 2020, was conducted. Data were obtained from the Surveillance, Epidemiology, and End Results Program, and data analysis was performed from August 2023 to March 2024.Residence in areas affected by persistent poverty is defined as a condition where 20% or more of the population has lived below the poverty level for approximately 30 years.All-cause and breast cancer-specific mortality.Among 312 145 patients (mean [SD] age, 61.9 [13.3] years), 20 007 (6.4%) lived in a CT with persistent poverty. Compared with individuals living in areas without persistent poverty, patients residing in persistently impoverished CTs were more likely to identify as Black (8735 of 20 007 [43.7%] vs 29 588 of 292 138 [10.1%]; P < .001) or Hispanic (2605 of 20 007 [13.0%] vs 23 792 of 292 138 [8.1%]; P < .001), and present with more-aggressive tumor characteristics, including higher grade disease, triple-negative breast cancer, and advanced stage. A higher proportion of patients residing in areas with persistent poverty underwent mastectomy and axillary lymph node dissection. Living in a persistently impoverished CT was associated with a higher risk of breast cancer-specific (adjusted hazard ratio [AHR], 1.10; 95% CI, 1.03-1.17) and all-cause (AHR, 1.13; 95% CI, 1.08-1.18) mortality. As early as 3 years following diagnosis, mortality risks diverged for both breast cancer-specific (rate ratio [RR], 1.80; 95% CI, 1.68-1.92) and all-cause (RR, 1.62; 95% CI, 1.56-1.70) mortality.In this cohort study of women aged 18 years or older diagnosed with stage I to III breast cancer between 2010 and 2018, living in neighborhoods characterized by persistent poverty had implications on tumor characteristics, surgical management, and mortality.