持续的邻里贫困和乳腺癌结果

与生活在没有持续贫困的社区相比，居住在社会经济上处于贫困社区中的乳腺癌患者通常会面临较差的结果（例如，死亡率）。检查持续的邻里贫困和乳房肿瘤特征，手术治疗和死亡率和死亡率和死亡率和死亡率。 2020年3月31日进行了。从2023年8月至2024年3月进行的监视，流行病学和最终结果计划中获得数据。多年），20007年（6.4％）生活在持续贫困的CT中。 Compared with individuals living in areas without persistent poverty, patients residing in persistently impoverished CTs were more likely to identify as Black (8735 of 20 007 [43.7%] vs 29 588 of 292 138 [10.1%]; P < .001) or Hispanic (2605 of 20 007 [13.0%] vs 23 792 of 292 138 [8.1%]; p <.001），并具有更侵略性的肿瘤特征，包括高级疾病，三阴性乳腺癌和晚期阶段。居住在持续贫困地区的患者中，较高比例进行了乳房切除术和腋窝淋巴结清扫术。生活在持续贫困的CT中与乳腺癌特异性的较高风险有关（调整后的危害比[AHR]，1.10; 95％CI，1.03-1.17）和全因（AHR，1.13; 95％CI，1.08-1.18）的死亡率。早在诊断后的3年后，乳腺癌特异性（RR]，1.80； 95％CI，1.68-1.92）和全因（RR，1.62; 95％CI，1.56-1.70）的死亡率风险都存在分歧（RR]，1.80； 95％CI，1.68-1.92）。持续的贫困对肿瘤特征，手术管理和死亡率有影响。

Patients with breast cancer residing in socioeconomically disadvantaged communities often face poorer outcomes (eg, mortality) compared with individuals living in neighborhoods without persistent poverty.To examine persistent neighborhood poverty and breast tumor characteristics, surgical treatment, and mortality.A retrospective cohort analysis of women aged 18 years or older diagnosed with stage I to III breast cancer between January 1, 2010, and December 31, 2018, and followed up until December 31, 2020, was conducted. Data were obtained from the Surveillance, Epidemiology, and End Results Program, and data analysis was performed from August 2023 to March 2024.Residence in areas affected by persistent poverty is defined as a condition where 20% or more of the population has lived below the poverty level for approximately 30 years.All-cause and breast cancer-specific mortality.Among 312 145 patients (mean [SD] age, 61.9 [13.3] years), 20 007 (6.4%) lived in a CT with persistent poverty. Compared with individuals living in areas without persistent poverty, patients residing in persistently impoverished CTs were more likely to identify as Black (8735 of 20 007 [43.7%] vs 29 588 of 292 138 [10.1%]; P < .001) or Hispanic (2605 of 20 007 [13.0%] vs 23 792 of 292 138 [8.1%]; P < .001), and present with more-aggressive tumor characteristics, including higher grade disease, triple-negative breast cancer, and advanced stage. A higher proportion of patients residing in areas with persistent poverty underwent mastectomy and axillary lymph node dissection. Living in a persistently impoverished CT was associated with a higher risk of breast cancer-specific (adjusted hazard ratio [AHR], 1.10; 95% CI, 1.03-1.17) and all-cause (AHR, 1.13; 95% CI, 1.08-1.18) mortality. As early as 3 years following diagnosis, mortality risks diverged for both breast cancer-specific (rate ratio [RR], 1.80; 95% CI, 1.68-1.92) and all-cause (RR, 1.62; 95% CI, 1.56-1.70) mortality.In this cohort study of women aged 18 years or older diagnosed with stage I to III breast cancer between 2010 and 2018, living in neighborhoods characterized by persistent poverty had implications on tumor characteristics, surgical management, and mortality.