“寡转移”疾病的概念表明局部疾病和广泛转移之间存在中间状态，这可能可以通过治愈性治疗策略进行治疗。转移局部治疗 (MLT) 可以通过多种技术来完成，例如立体定向消融放射治疗 (SABR)、射频消融 (RFA)、微波消融 (MWA)、冷冻消融或手术转移切除术。将 MLT 纳入转移性肉瘤患者的多学科治疗是很复杂的。回顾性研究支持根据患者状况、疾病生物学、组织学类型和疾病负担等因素考虑对选定的患者进行 MLT。关于 MLT 的类型和时间的决定应在多学科讨论后做出，包括放射肿瘤学家、外科和骨科肿瘤学家、肿瘤内科医生和介入放射学，以在治疗决策之前探索所有选择。所有 MLT 技术都有优点和缺点，应在专门护理复杂肿瘤患者的中心进行，在那里可以同时或依次为每位患者探索各种选择。未来的研究需要评估生活质量和患者报告的结果，以充分调整患者目标和最佳结果。本文回顾了可能有利于使用 MLT 的医疗场景，评估了与这些不同技术相关的独特优点和缺点，并分析了关键系列的研究结果，以全面了解其在临床实践中的作用。© 2024。Crown。

The concept of "oligometastatic" disease suggests the presence of intermediate states between localized disease and widespread metastases, which may be potentially treatable with curative therapeutic strategies. Metastases local therapy (MLT) can be accomplished through various techniques such as stereotactic ablative radiotherapy (SABR), radiofrequency ablation (RFA), microwave ablation (MWA), cryoablation, or surgical metastasectomy. The incorporation of MLT in the multidisciplinary treatment of patients with metastatic sarcoma is complex. Retrospective studies support consideration of MLT for selected patients based on factors such as patient condition, disease biology, histologic type, and disease burden. Decisions regarding type and timing of MLT should be made after multidisciplinary discussion including radiation oncologists, surgical and orthopedic oncologists, medical oncologists, and interventional radiology to explore all options before treatment decsions. All MLT techniques have advantages and disadvantages and should be performed in centers specialized in the care of complex oncology patients where various options can be explored concurrently or sequentially for each patient. Future studies evaluating quality of life and patient-reported outcomes are necessary to adequately align patient goals and optimal outcomes. This article reviews the medical scenarios that may benefit the use of MLT, evaluates the distinct advantages and disadvantages associated with these various techniques, and analyzes the findings from pivotal series to provide a comprehensive understanding of its role in clinical practice.© 2024. Crown.