比较接受电视辅助胸腔镜肺癌手术 (VATS) 的肌肉减少症和非肌肉减少症患者术后早期患者报告的结果。本研究中使用的数据来自 2017 年 11 月的一项纵向前瞻性研究 (CN-PRO-Lung 1) 2020 年 1 月。在术前计算机断层扫描中测量 L3 椎骨水平的骨骼肌指数，以根据既定阈值识别肌肉减少症。症状严重程度和功能障碍状态以具有临床相关中度至重度评分（0-10 分）的患者比例进行报告，这些评分是通过使用 MD 安德森肺癌症状清单在基线、每日术后住院和每周进行测量的。出院后长达 4 周。比较肌肉减少症组和非肌肉减少症组的症状严重程度、功能状态和术后临床结果。这项研究包括 125 名因肺癌接受 VATS 的患者。 34 名 (27.2%) 患者发现肌肉减少症。肌肉减少症患者出院时报告有更多的中度至重度疼痛（P = 0.002），出院后 4 周内有更多的中度至重度疲劳（P = 0.027）。此外，肌肉减少症患者的疼痛（P = 0.002）和疲劳（P = 0.007）恢复时间比非肌肉减少症患者更长。同时，术后临床结果组间差异均无统计学意义（均P > 0.05）。与非肌肉减少症患者相比，接受肺癌VATS手术的肌肉减少症患者术后早期可能会出现更多的疼痛和疲劳，症状恢复时间也更长。 period.© 2024。外科肿瘤学会。

To compare early postoperative patient-reported outcomes between sarcopenic and nonsarcopenic patients undergoing video-assisted thoracoscopic surgery (VATS) for lung cancer.The data used in this study were acquired from a longitudinal prospective study (CN-PRO-Lung 1) between November 2017 and January 2020. Skeletal muscle index was measured at L3 vertebral level on preoperative computed tomography to identify sarcopenia based on an established threshold. Symptoms severity and status of functional impairments were reported as proportions of patients with clinically relevant moderate-to-severe scores on 0-10 scales, which were measured by using the MD Anderson Symptom Inventory-Lung Cancer at baseline, daily postoperative hospitalization, and weekly after discharge up to 4 weeks. Symptom severity, functional status, and postoperative clinical outcomes were compared between the sarcopenia and nonsarcopenia groups.This study included 125 patients undergoing VATS for lung cancer. Sarcopenia was identified in 34 (27.2%) patients. Sarcopenic patients reported more moderate-to-severe pain (P = 0.002) at discharge and more moderate-to-severe fatigue (P = 0.027) during the 4 weeks after discharge. Besides, sarcopenic patients had a longer recovery time from both pain (P = 0.002) and fatigue (P = 0.007) than nonsarcopenic patients. Meanwhile, no significant between-group difference was found in the postoperative clinical outcomes (all P > 0.05).Sarcopenic patients undergoing VATS for lung cancer may have more pain and fatigue, as well as longer symptoms recovery time than nonsarcopenic patients during the early postoperative period.© 2024. Society of Surgical Oncology.