研究动态
Articles below are published ahead of final publication in an issue. Please cite articles in the following format: authors, (year), title, journal, DOI.

食管癌中的外泌体:在癌症进展、诊断、预后和治疗中具有前景的纳米载体。

Exosomes in esophageal cancer: Promising nanocarriers in cancer progression, diagnosis, prognosis, and therapy.

发表日期:2024
作者: Ligong Yuan, Haoran Ji, Yang Cao, Hang Yi, Qihao Leng, Jie Zhou, Xinyu Mei
来源: Wires Nanomed Nanobi

摘要:

食管癌(EC)是全世界最致命的癌症之一。为了改善 EC 的预后,迫切需要早期 EC 的灵敏检测方式和有效的治疗方法。外泌体是用于细胞间通讯的小囊泡,介导包括癌症进展在内的许多生物反应,这不仅是用于诊断和预后的有前途的生物标志物,而且还是 EC 的治疗工具。本综述概述了外泌体与 EC 进展之间的关系,以及外泌体在 EC 诊断、预后和治疗中的应用。本文分类为:治疗方法和药物发现 > 肿瘤疾病纳米医学。© 2024 Wiley periodicals LLC。
Esophageal cancer (EC) is one of the most fatal cancers all over the world. Sensitive detection modalities for early-stage EC and efficient treatment methods are urgently needed for the improvement of the prognosis of EC. Exosomes are small vesicles for intercellular communication, mediating many biological responses including cancer progression, which are not only promising biomarkers for diagnosis and prognosis but also therapeutic tools for EC. This review provides an overview of the relationships between exosomes and EC progression, as well as the application of exosomes in the diagnosis, prognosis, and treatment of EC. This article is categorized under: Therapeutic Approaches and Drug Discovery > Nanomedicine for Oncologic Disease.© 2024 Wiley Periodicals LLC.