运动对患有癌症疼痛的成人的影响:系统评价和网络荟萃分析。
Effects of exercise in adults with cancer pain: a systematic review and Network meta-analysis.
发表日期:2024 Aug 30
作者:
Jie Wang, Meiling Lv, Hongpeng Li, Dongqing Guo, Xin Chu
来源:
JOURNAL OF PAIN AND SYMPTOM MANAGEMENT
摘要:
疼痛是癌症患者最常见的症状之一,影响患者的身体、心理、行为、社会关系等各个方面。先前的研究已证明运动对癌性疼痛有效,但最佳运动方式仍未知。本研究旨在比较不同运动干预措施对成人癌性疼痛的效果。从报告运动效果的医学文献数据库中筛选出随机对照试验这项研究包括患有癌症疼痛的成年人。文献筛选和数据提取由两名研究人员独立进行。采用Cochrane偏倚评估2.0评估文献质量,采用Stata 15.0软件进行网络荟萃分析。共纳入41项研究,涉及3537例癌痛患者。涉及的运动类型包括有氧运动、中等强度持续训练、高强度间歇训练、阻力运动、身心运动和综合运动计划(CEP)。结果表明,CEP 在缓解癌症患者疼痛强度方面比常规护理更有效 [SMD=-1.96,95%CI (-3.47, -0.44)] (SUCRA=97.9%)。身心锻炼在减少癌症患者疼痛干扰方面优于常规护理 [SMD=-0.65, 95% CI (-1.21, -0.09)] (SUCRA=83.8%)。目前的证据表明,CEP 是缓解疼痛的最佳方法癌症患者的疼痛强度较大,而身心锻炼是减少癌症患者疼痛干扰的最佳方法。由于纳入研究的数量和质量有限,上述结论还需要更多高质量研究的进一步验证。版权所有©2024。Elsevier Inc.出版。
Pain is one of the most common symptoms of cancer patients, affecting the patient's physical, psychological, behavioral, social relations and other aspects. Previous studies have demonstrated that exercise is effective for cancer pain, and the optimal exercise is still unknown.This study aimed to compare the effects of different exercise interventions on cancer pain in adults.Randomized control trials identified from medical literature databases that reported effects of exercise in adults with cancer pain were included in this study. Literature screening and data extraction were conducted independently by two researchers. Cochrane Bias Assessment 2.0 was used to assess the quality of the literature, and Stata 15.0 software was used for Network meta-analysis.Forty-one studies were included, involving 3537 patients with cancer pain. The types of exercise involved included aerobic exercise, medium intensity continuous training, high-intensity interval training, resistance exercise, mind-body exercise and comprehensive exercise program (CEP). The results suggested that CEP was more effective than the usual care in relieving pain intensity in cancer patients [SMD=-1.96,95%CI (-3.47, -0.44)] (SUCRA=97.9%). Mind-body exercise outperformed usual care in reducing pain interference in cancer patients [SMD = -0.65, 95% CI (-1.21, -0.09)] (SUCRA=83.8%).Current evidence shows that CEP is the best way to relieve the pain intensity of cancer patients, and mind-body exercise is the best way to reduce pain interference of cancer patients. Due to the limited number and quality of the included studies, the above conclusions need to be further verified by more high-quality studies.Copyright © 2024. Published by Elsevier Inc.