金属和金属氧化物的纳米颗粒（NP）构成了单金属纳米颗粒（MNP）技术的重要组成部分。在过去的十年中，纳米颗粒最令人着迷和最深入的用途被发现在生物医学领域，这证明了这些颗粒的治疗潜力。纳米技术在包括生物医学在内的各个行业的应用已经取得了重大进展。在生物医学中，纳米粒子最重要的两个应用是疾病的诊断和治疗。鉴于其提供特定药物的能力，这些下一代纳米粒子为多种疾病提供安全有效的药物疗法。硒纳米颗粒 (SeNP) 和二氧化钛 (TiO2) 纳米颗粒为各种应用提供了潜在的治疗方法，包括护发和癌症治疗。 SeNP 有助于应对非生物胁迫、植物病害和生长，而 TiO2 NP 则增强生物成像和药物输送。本综合综述重点关注 Se（金属基）和 TiO2（金属氧化物基）等 MNP。它涵盖了它们的合成方法、纳米级物理化学性质以及应用纳米技术各个领域（包括生物医学）中特定工业应用的定义。© 2024 作者。约翰·威利 (John Wiley) 出版的《保健科学》

The nanoparticles (NPs) of metals and metal oxides constitute significant components of technology in terms of monometallic NPs (MNPs). Over the last decade, the most fascinating and in-depth uses of NPs have been found in the biomedical field, which has demonstrated the therapeutic potential of these particles. Significant strides have been made in the application of nanotechnology across various industries, including biomedical sciences. In biomedicine, two of the most important applications of NPs are in the diagnosis and treatment of disease. Given their ability to deliver specific drugs, these next-generation NPs provide safe and effective pharmacotherapies for a wide range of disorders. Selenium nanoparticles (SeNPs) and titanium dioxide (TiO2) NPs offer potential treatments for various applications, including hair care and cancer treatment. SeNPs help with abiotic stress, plant disease, and growth, while TiO2 NPs enhance bio-imaging and drug delivery. This comprehensive review focuses on MNPs like Se (metal-based) and TiO2 (metal-oxide based). It covers their synthesis methods, nanoscale physicochemical properties, and the definition of specific industrial applications in various fields of applied nanotechnology, including biomedicine.© 2024 The Author(s). Health Care Science published by John Wiley & Sons Ltd on behalf of Tsinghua University Press.