研究动态
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轻步行联合关节镜手术对足踝骨关节炎患者骨密度的影响

Effect of light walking combined with arthroscopic surgery on bone mineral density in patients with foot and ankle osteoarthritis.

发表日期:2024 Aug 30
作者: Xiaoyan Li, Kangwon You
来源: Arthritis & Rheumatology

摘要:

目的观察轻步行联合关节镜手术对踝关节关节炎患者的疗效及骨密度(BMD)的影响。方法回顾性选取180例踝关节关节炎患者,根据治疗方法分为对照组(A组)和实验组(B组),每组90例。 A组采用常规开放手术治疗,B组采用轻步行联合关节镜手术治疗。比较两组治疗前后的AOFAS踝后足评分等量表。同时比较患者治疗前后的骨密度和肿瘤细胞坏死因子-α(TNF-α)等炎症因子水平。结果 轻度步行联合关节镜手术组的Kofoed和AOFAS量表评分高于常规治疗组(P < 0.05),疼痛视觉模拟VAS评分低于常规治疗组(P < 0.05)。 B组术后BMD增加明显较高(P < 0.05)。 PDGF骨生长因子与BMD之间的R值为0.957,VEGF生长因子与BMD之间的R值为0.903。患者年龄和 BMD 之间的 R 值为 -0.936,患者 BMI 和 BMD 之间的 R 值为 -0.913。 B组的治疗有效率为96.7%。结论结果证明轻步行联合关节镜手术适合踝关节关节炎患者的手术治疗,具有较好的治疗效果,并使患者的BMD水平得到改善。© 2024 The Authors.
ObjectiveTo observe the effect of light walking combined with arthroscopic surgery on the efficacy and Bone Mineral Density (BMD) of patients with ankle arthritis. Methods 180 patients with ankle arthritis were retrospectively selected, who were divided into a control group (Group A) and an experimental group (Group B) according to treatment methods, with 90 patients in each group. Group A was treated with conventional open surgery and Group B was treated with light walking combined with arthroscopic surgery. The two groups were compared before and after treatment on scales such as the AOFAS ankle hindfoot score. Meanwhile, the patients' BMD and levels of inflammatory factors such as tumor cell necrosis factor-α (TNF-α) were compared before and after treatment. Results The Kofoed and AOFAS scale scores were higher for mild walking combined with arthroscopic surgery than for conventional treatment (P < 0.05), and their pain visual analogue VAS scores were lower than for conventional treatment (P < 0.05). In Group B, the postoperative BMD increase was significantly higher (P < 0.05). The R-value between PDGF bone growth factor and BMD was 0.957 and the R-value between VEGF growth factor and BMD was 0.903. The R-value between patient age and BMD was -0.936 and the R-value between patient BMI and BMD was -0.913. The treatment efficiency in Group B was 96.7 %. Conclusion The results prove that light walking combined with arthroscopic surgery is suitable for the surgical treatment of patients with ankle arthritis because it has a better therapeutic effect and makes patients' BMD level improved.© 2024 The Authors.