蝶骨眶脑膜瘤 (SOM) 是蝶骨翼脑膜瘤的一种独特变体，其特征在于其骨浸润和颅骨眶受累的倾向。 SOM 的误诊和复发率相当高。旨在阐明 SOM 的临床、放射学和病理学特征。回顾 100 名 SOM 患者的电子病历、组织病理学、放射学图像和随访信息。在 100 名患者中（28 名男性） ，72 名女性）患有 SOM，平均年龄为 46.8±12.6 岁，普遍症状为眼球突出（99%）。所有CT扫描均显示骨质增生，其中89.3%的骨质增生边缘不规则。在MRI扫描中，所有患者均观察到硬脑膜尾征，颅眶肿瘤常穿透颞肌（74.1%）、眼外肌（74.1%）和泪腺（63%）。 100例患者全部接受了手术干预，其中62例接受了术后放疗。 Ⅰ级切除的复发率较低（16.7%），随着放疗的加入进一步降低（13.9%）。相比之下，所有未经放疗而进行 II 级或更高级别切除的患者均出现复发，表明肿瘤切除不完全的风险较高。病理检查显示，眶内切片的肿瘤密度与眶内SOM肿瘤相当，纤维密度增加，但血管分布减少。SOM的放射学特征包括颅眶肿瘤、蝶骨翼骨质增生且边缘不规则、硬脑膜尾征。 。建议结合大体全切除和辅助放疗以尽量减少复发率。颅内 SOM 肿瘤往往比眶内切片更软且更容易出血，因此需要手术精度。© 2024。作者。

Spheno-orbital meningioma (SOM) represents a unique variant of sphenoid wing meningiomas, distinguished by its propensity for bone infiltration and cranio-orbital involvement. SOM exhibits a considerable incidence of misdiagnosis and recurrence.To elucidate the clinical, radiological, and pathological characteristics of SOM.Review of electronic medical records, histopathology, radiological images and follow-up information of 100 SOM patients.Of the 100 patients (28 males, 72 females) with SOM, mean age was 46.8 ± 12.6 years and prevalent symptoms were proptosis (99%). All the CT scans showed hyperostosis with 89.3% of the hyperostosis having an irregular edge. In MRI scans, dural tail sign was observed across all patients and the cranio-orbital tumors often penetrated temporal muscle (74.1%), extraocular muscle (74.1%) and lacrimal gland (63%). All the 100 patients underwent surgical intervention, and among them, 62 individuals received postoperative radiotherapy. Grade I resections had a lower recurrence rate(16.7%), which further decreased with the addition of radiotherapy(13.9%). In contrast, all patients with grade II or higher grade resections without radiotherapy experienced recurrence, indicating a higher risk associated with less complete tumor removal. The pathological examination revealed that intraorbital sections exhibited comparable tumor density to intraorbital SOM tumors, along with increased fibrous density but decreased vascular distribution.Radiological characteristics of SOM included cranio-orbital tumors, hyperostosis of the sphenoid wing with an irregular edge, and dural tail sign. Combination of gross total resection and adjuvant radiotherapy was recommended to minimize recurrence rate. Intracranial SOM tumors tended to be softer and more bleed-prone than intraorbital sections, necessitating surgical precision.© 2024. The Author(s).