癌症治疗面临着越来越严峻的挑战，其特点是围绕体细胞突变、精准肿瘤学和大量大数据的广泛技术和研究工作。尽管有如此丰富的信息，但治愈癌症的探索往往显得更加难以捉摸，“抗癌战争”尚未取得决定性的胜利。一个特别紧迫的问题是肿瘤治疗耐药性的发展，凸显了对创新方法的迫切需要。进化论、量子生物学和系统生物学为推进实验性癌症研究提供了一个有前途的框架。通过整合理论研究、转化方法和灵活的多学科临床研究，有可能增强当前的治疗策略并改善癌症患者的治疗结果。在进化、量子、熵和混沌原理与肿瘤学之间建立更紧密的联系可能会带来更有效的治疗方法，利用对肿瘤进化动力学的理解，为控制和减轻癌症的新方法铺平道路。实现这些目标需要致力于以肿瘤学研究和临床工作为核心的多学科和跨专业合作。这需要消除学科之间的隔阂，鼓励开放沟通和数据共享，并从研究项目一开始就整合不同的观点和专业知识。接受新的科学发现并对患者对治疗的反应做出反应也至关重要。这些策略是使肿瘤学领域保持在有效癌症管理前沿的关键，确保患者获得最个性化和有效的护理。最终，这种方法旨在突破对癌症理解的界限，将其视为一种可控制的慢性病，​​旨在延长预期寿命并提高患者的生活质量。版权所有 © 2024 Casotti, Meira, Zetum, Campanharo, Silva, Giacinti, Silva,莫拉、巴博萨、阿尔托、毛里西奥、戈斯、阿尔维斯、利尼亚雷斯、文托里姆、瓜托利尼、桑托斯、埃雷拉、格罗斯曼、卡瓦略、保拉、索萨、费希内和卢罗。

Cancer therapy is facing increasingly significant challenges, marked by a wide range of techniques and research efforts centered around somatic mutations, precision oncology, and the vast amount of big data. Despite this abundance of information, the quest to cure cancer often seems more elusive, with the "war on cancer" yet to deliver a definitive victory. A particularly pressing issue is the development of tumor treatment resistance, highlighting the urgent need for innovative approaches. Evolutionary, Quantum Biology and System Biology offer a promising framework for advancing experimental cancer research. By integrating theoretical studies, translational methods, and flexible multidisciplinary clinical research, there's potential to enhance current treatment strategies and improve outcomes for cancer patients. Establishing stronger links between evolutionary, quantum, entropy and chaos principles and oncology could lead to more effective treatments that leverage an understanding of the tumor's evolutionary dynamics, paving the way for novel methods to control and mitigate cancer. Achieving these objectives necessitates a commitment to multidisciplinary and interprofessional collaboration at the heart of both research and clinical endeavors in oncology. This entails dismantling silos between disciplines, encouraging open communication and data sharing, and integrating diverse viewpoints and expertise from the outset of research projects. Being receptive to new scientific discoveries and responsive to how patients react to treatments is also crucial. Such strategies are key to keeping the field of oncology at the forefront of effective cancer management, ensuring patients receive the most personalized and effective care. Ultimately, this approach aims to push the boundaries of cancer understanding, treating it as a manageable chronic condition, aiming to extend life expectancy and enhance patient quality of life.Copyright © 2024 Casotti, Meira, Zetum, Campanharo, Silva, Giacinti, Silva, Moura, Barbosa, Altoé, Mauricio, Góes, Alves, Linhares, Ventorim, Guaitolini, Santos, Errera, Groisman, Carvalho, Paula, Sousa, Fechine and Louro.