感染 COVID-19 并接种疫苗后出现肾小球疾病 (GD) 的报告越来越多。目前关于 COVID-19 感染或疫苗接种与 GD 之间可能存在联系的证据是相互矛盾的。本研究对研究进行了范围界定审查，以描述 COVID-19 感染和疫苗接种与 GD 之间的关系以及常见的管理策略和总体结果疾病，以确定知识差距并指导进一步的研究。2022 年 9 月 5 日之前以英文发表的所有原始研究都被考虑纳入该综述。排除标准包括动物研究、尸检研究以及涉及儿科患者（< 16 岁）、移植受者、肾小球疾病复发、伴有癌症或可能导致肾小球疾病的非 COVID-19 感染的数据，或未接受肾活检。搜索的五个电子数据库是 MEDLINE、PubMed、Scopus、EMBASE 和 Cochrane。使用布尔运算符“AND”组合了与 COVID-19 和肾小球疾病相关的两个单独的搜索字符串。使用过滤器将出版物限制为以英文发表的原始研究报告。每个数据库的搜索结果被导入 Covidence 软件 ( www.covidence.org ) 并用于重复数据删除、文章筛选和数据提取。使用描述性分析来总结人口统计、诊断和治疗结果。去除重复后，筛选出 6853 个标题和摘要。在纳入的 188 项研究中，106 项研究描述了 341 名感染 COVID-19 后出现 GD 的患者，82 项研究描述了 146 名接种 COVID-19 疫苗后出现 GD 的患者。 IgA 肾病是接种 COVID-19 疫苗后报告的最常见的 GD 病理，其中 GD 在 mRNA 疫苗接种后最常见。塌陷性局灶节段性肾小球硬化症是 COVID-19 感染后最常见的 GD。 GD 的免疫抑制治疗在疫苗队列中比在感染队列中更常见。尽管世界各地有大量的 COVID-19 感染和疫苗接种，但我们对 GD 与 COVID-19 感染和疫苗接种相关的了解仍然很薄弱，还有更多的研究需要更好地了解可能的关系。© 2024。Crown。

There are increasing reports of glomerular disease (GD) following COVID-19 infection and vaccination. Current evidence on the possible link between COVID-19 infection or vaccination and GD is conflicting.The present study undertakes a scoping review of research to describe the relationship between COVID-19 infection and vaccination with GD and the common management strategies and overall outcomes of the disease to identify knowledge gaps and guide further research.All original research studies published in English until 5th September 2022 were considered for inclusion in the review. Exclusion criteria were animal studies, autopsy studies, and data involving patients who were paediatric patients (< 16 years), were transplant recipients, had a recurrence of glomerular disease, had concomitant cancer or non-COVID-19 infection which may cause glomerular disease, or did not receive a renal biopsy.The five electronic databases searched were MEDLINE, PubMed, Scopus, EMBASE, and Cochrane.Two separate search strings related to COVID-19, and glomerular disease were combined using the Boolean operator 'AND'. Filters were used to limit publications to original research studies published in English. Search results from each database were imported into Covidence software ( www.covidence.org ) and used for de-duplication, article screening, and data extraction. Descriptive analyses were used to summarise demographics, diagnoses, and treatment outcomes.After removing duplicates, 6853 titles and abstracts were screened. Of the 188 studies included, 106 studies described 341 patients with GD following COVID-19 infection and 82 described 146 patients with GD following a COVID-19 vaccination. IgA nephropathy was the most common GD pathology reported following COVID-19 vaccination with GD most common following mRNA vaccines. Collapsing focal segmental glomerulosclerosis was the most common GD following COVID-19 infection. Immunosuppressive treatment of GD was more common in the vaccine cohort than in the infection cohort.Despite the significant number of COVID-19 infections and vaccinations around the world, our understanding of GD associated with COVID-19 infection and vaccination remains poor, and more research is needed to understand the possible relationship better.© 2024. Crown.