旨在评估女性不孕症患者的用餐频率与辅助生殖技术（ART）结果之间的关系。这项队列研究于 2022 年 2 月至 2024 年 1 月在东京医科大学医院进行。总体而言，101 名患有不孕问题且没有中风、心脏病、癌症或 1 型或 2 型糖尿病病史的女性患者参加了这项研究。从问卷中提取的因素包括人口统计信息、ART前和20岁时的进餐频率、吸烟状况和饮酒状况。其他因素的数据，包括年龄、体重指数、抗苗勒氏管激素水平和产次史，均从病历中收集。评估的临床结果包括移植胚胎的数量、临床妊娠、持续妊娠、活产和流产。在调整潜在的混杂因素后，包括年龄、吸烟状况、饮酒状况、体重指数、抗苗勒氏管激素水平和产次历史，对 ART 结果进行了多变量分析。根据每周早餐、午餐和晚餐的食用频率将患者分为几组。每周吃 6-7 次早餐的患者通过 ART 受孕的活产率和流产率明显更高。在 ART 之前每周吃 6-7 次早餐与 ART 后的成功率增加相关艺术。这凸显了定期吃早餐对于优化 ART 效果的潜在重要性。版权所有 © 2024 Elsevier Inc. 保留所有权利。

To assess the relationship between meal consumption frequency and assisted reproductive technology (ART) outcomes among female patients with infertility.This cohort study was conducted from February 2022 to January 2024 at Tokyo Medical University Hospital. Overall, 101 female patients with infertility issues and without a history of stroke, heart disease, cancer, or type 1 or type 2 diabetes were enrolled in this study. The factors extracted from the questionnaire included demographic information, meal consumption frequency before ART and at 20 years of age, smoking status, and alcohol consumption status. Data on other factors, including age, body mass index, anti-Müllerian hormone level, and parity history, were collected from medical records. The assessed clinical outcomes included number of transplanted embryos, clinical pregnancies, ongoing pregnancies, live births, and miscarriages.After adjusting for potential confounding factors, including age, smoking status, alcohol consumption status, body mass index, anti-Müllerian hormone level, and parity history, a multivariate analysis of ART outcomes was performed. Patients were categorized into groups based on the frequency of weekly consumption of breakfast, lunch, and dinner. Patients who consumed breakfast 6-7 times a week were significantly more likely to have higher rates of live birth and lower rates of miscarriage in pregnancies conceived through ART.Consumption of breakfast 6-7 times a week before ART was associated with increased success rates following ART. This highlights the potential importance of regular breakfast consumption for optimizing ART outcomes.Copyright © 2024 Elsevier Inc. All rights reserved.