乳腺癌（BC）是世界上癌症相关死亡的重要原因。三阴性乳腺癌（TNBC）作为BC中预后最差的亚型，严重威胁人类生命和健康。近年来，越来越多的研究旨在设计和开发用于诊断和治疗 TNBC 的纳米材料。本研究旨在通过文献计量分析，综合评价纳米材料在TNBC中的应用现状和趋势。从Web of Science核心合集（WOSCC）数据库中检索关注纳米材料与癌症的研究，并选择符合纳入标准的相关文献纳入本研究。 VOSviewer 和 CiteSpace 用于对所包含的出版物进行文献计量和视觉分析。总共纳入 2338 项研究。从2010年到2024年，每年的出版物数量有所增加。中国、美国和印度是该领域的领先国家，分别占出版物总量的66.1%、11.5%和7.2%。中国科学院和李亚平分别是最有影响力的机构和作者。 Journal of Controlled Release 被认为是生产力最高的期刊。 《Cancer Research》被认为是同被引用次数最多的期刊。与纳米材料相关的药物递送和抗癌机制被认为是研究最广泛的方面，绿色合成和抗癌机制也是近期的研究热点。本研究总结了出版物的特点，确定了纳米材料在癌症应用中最具影响力的国家、机构、作者、期刊、热点和趋势。这些发现为了解这一动态领域的现状和未来方向提供了宝贵的见解。© 2024。受控释放协会。

Breast cancer (BC) is an important cause of cancer-related death in the world. As a subtype of BC with the worst prognosis, triple-negative breast cancer (TNBC) is a serious threat to human life and health. In recent years, there has been an increasing amount of research aimed at designing and developing nanomaterials for the diagnosis and treatment of TNBC. The purpose of this study was to comprehensively evaluate the current status and trend of the application of nanomaterials in TNBC through bibliometric analysis. Studies focusing on nanomaterials and cancer were searched from the Web of Science core collection (WOSCC) database, and relevant literature meeting the inclusion criteria was selected for inclusion in the study. VOSviewer and CiteSpace were used to perform bibliometric and visual analysis of the included publications. A total of 2338 studies were included. Annual publications have increased from 2010 to 2024. China, the United States and India were the leading countries in the field, accounting for 66.1%, 11.5% and 7.2% of publications, respectively. The Chinese Academy of Sciences and Li Yaping were the most influential institutions and authors, respectively. Journal of Controlled Release was considered the most productive journal. Cancer Research was considered to be the most co-cited journal. Drug delivery and anti-cancer mechanisms related to nanomaterials were considered to be the most widely studied aspects, and green synthesis and anti-cancer mechanisms were also recent research hotspots. In this study, the characteristics of publications were summarized, and the most influential countries, institutions, authors, journals, hot spots and trends in the application of nanomaterials in cancer were identified. These findings provide valuable insights into the current state and future direction of this dynamic field.© 2024. Controlled Release Society.