环境污染物和害虫密切相关。
Environmental pollutants and bad bugs work hand in glove.
发表日期：2024 Oct
作者：
Dingjiacheng Jia, Shujie Chen
来源：
Trends in Cancer
摘要：
“坏细菌”可能会改变环境污染物的毒代动力学，从而加剧化学诱导的肿瘤发生。最近，罗杰等人。报道称，特定的肠道微生物群可以将亚硝胺化合物代谢为有毒的氧化产物，从而加剧膀胱癌的发生和进展。这些发现对于通过肠道微生物群干预肿瘤具有重要意义。版权所有 © 2024 Elsevier Inc. 保留所有权利。
'Bad bacteria' could alter the toxicokinetics of environmental pollutants, thereby exacerbating chemically induced tumorigenesis. Recently, Roje et al. reported that specific gut microbiota can metabolize nitrosamine compounds to a toxic oxidation product, aggravating bladder cancer development and progression. These findings have important implications for tumor intervention through the gut microbiota.Copyright © 2024 Elsevier Inc. All rights reserved.