从1990年至2021年
Global burden of benign prostatic hyperplasia, urinary tract infections, urolithiasis, bladder cancer, kidney cancer, and prostate cancer from 1990 to 2021
影响因子:22.90000
分区:医学1区 Top / 医学:内科1区
发表日期:2024 Sep 18
作者:
Hao Zi, Meng-Yang Liu, Li-Sha Luo, Qiao Huang, Peng-Cheng Luo, Hang-Hang Luan, Jiao Huang, Dan-Qi Wang, Yong-Bo Wang, Yuan-Yuan Zhang, Ren-Peng Yu, Yi-Tong Li, Hang Zheng, Tong-Zu Liu, Yu Fan, Xian-Tao Zeng
摘要
常见泌尿科疾病的负担,包括良性前列腺增生(BPH),尿路感染(UTI),尿道症,膀胱癌,肾脏癌和前列腺癌,在地理位置上和特定地区都在不同。至关重要的是,必须对泌尿外科疾病的全球负担进行全面,精确的评估。我们获得了有关上述泌尿外科疾病的发病率,流行率,死亡率和残疾调整的生命年(DALYS)的数据,该数据是根据年龄,性别,位置和疾病的全球责任(GBD)的社会(GBD)的纽带(分析)。指数(SDI)和可归因的风险因素。使用估计的年百分比变化(EAPC)以及95%的置信区间(CI)评估了随着时间的负担的趋势。2021年,BPH和UTI是年龄标准化的发生率(ASIR)的主要原因(ASIR)和年龄标准化的患病率(ASPR),速度(ASPR),率为5531.8888和2782.59 ever 100,000 severss and Inspr。前列腺癌是年龄标准化死亡率(ASMR)和年龄标准化的达利率(ASDR)的主要原因,分别为每100,000人12.63和217.83。从1990年到2021年,UTI的ASIR,ASPR,ASMR和ASDR的趋势向上趋势,而尿石症显示出下降的趋势。中间和低中型SDI五分位数水平表现出与UTI,尿道病和BPH相关的发病率,患病率,死亡率和达利人的发病率,而高和高中SDI五分位数的发病率较高,三种癌症的速率更高。这六种泌尿科疾病的负担表现出各种年龄和性别分布模式。在2021年,高体重指数(BMI)在全球范围内造成20.07%的肾脏癌死亡,而吸烟占膀胱癌死亡的26.48%,而前列腺癌死亡的3.00%。6种泌尿药疾病的全球负担引起了巨大的公共卫生挑战。紧急国际合作对于提高泌尿科疾病管理,涵盖有效诊断筛查工具的开发以及实施高质量预防和治疗策略至关重要。
Abstract
The burden of common urologic diseases, including benign prostatic hyperplasia (BPH), urinary tract infections (UTI), urolithiasis, bladder cancer, kidney cancer, and prostate cancer, varies both geographically and within specific regions. It is essential to conduct a comprehensive and precise assessment of the global burden of urologic diseases.We obtained data on incidence, prevalence, mortality, and disability-adjusted life-years (DALYs) for the aforementioned urologic diseases by age, sex, location, and year from the Global Burden of Disease (GBD) 2021. We analyzed the burden associated with urologic diseases based on socio-demographic index (SDI) and attributable risk factors. The trends in burden over time were assessed using estimated annual percentage changes (EAPC) along with a 95% confidence interval (CI).In 2021, BPH and UTI were the leading causes of age-standardized incidence rate (ASIR) and age-standardized prevalence rate (ASPR), with rates of 5531.88 and 2782.59 per 100,000 persons, respectively. Prostate cancer was the leading cause of both age-standardized mortality rate (ASMR) and age-standardized DALYs rate (ASDR), with rates of 12.63 and 217.83 per 100,000 persons, respectively. From 1990 to 2021, there was an upward trend in ASIR, ASPR, ASMR, and ASDR for UTI, while urolithiasis showed a downward trend. The middle and low-middle SDI quintile levels exhibited higher incidence, prevalence, mortality, and DALYs related to UTI, urolithiasis, and BPH, while the high and high-middle SDI quintile levels showed higher rates for the three cancers. The burden of these six urologic diseases displayed diverse age and sex distribution patterns. In 2021, a high body mass index (BMI) contributed to 20.07% of kidney cancer deaths worldwide, while smoking accounted for 26.48% of bladder cancer deaths and 3.00% of prostate cancer deaths.The global burden of 6 urologic diseases presents a significant public health challenge. Urgent international collaboration is essential to advance the improvement of urologic disease management, encompassing the development of effective diagnostic screening tools and the implementation of high-quality prevention and treatment strategies.