对接受开颅手术的脑肿瘤患者进行深静脉血栓 (DVT) 双重超声筛查 (DUS) 的频率因中心而异。我们评估了增加 DUS 倾向的临床条件，重点关注肿瘤类型。这是一项单中心回顾性分析，旨在评估颅内肿瘤类型与 DVT 之间的关系，作为 DUS 的主要决策指标。初步分析调查了肿瘤病理学与术前 DVT 之间的关联，二次分析调查了术后 DVT 的发展。两项分析均定义并纳入了混杂因素。在 1478 名患者中，751 名患者术前患有 DUS，35 名患者 (5%) 患有 DVT。恶性胶质瘤患者与良性肿瘤患者（比值比 [OR；95% CI]：1.68 [0.65，4.35]，P = 0.29）或转移性肿瘤与良性肿瘤患者（OR ：2.10；95% CI：0.75-5.89；P = 0.16）。在术前 DUS 阴性的患者中，93 例接受了术后评估，20 例（22%）被诊断为术后 DVT。与良性肿瘤相比，恶性胶质瘤或（OR：1.69；95% CI：0.36-7.84；P = 0.50）转移性肿瘤（OR：1.84；95% CI：0.29-11.5；P = 0.52）与术后 DVT 无关。肿瘤病理学可能不会增加 DVT 风险，并且可能不是选择 DUS 筛查患者的良好指标。选择性术前 DUS 中 DVT 的发生率与对所有患者进行 DUS 的研究相似。需要在多个机构进行进一步研究来制定脑肿瘤手术中 DUS 的标准。版权所有 © 2024 Wolters Kluwer Health, Inc. 保留所有权利。

The frequency of duplex ultrasound screening (DUS) for deep vein thrombosis (DVT) in patients with brain tumors undergoing craniotomy is center-specific. We evaluated clinical conditions that increase the tendency to perform DUS, focusing on tumor type.This is a single-center retrospective analysis to assess the association of intracranial tumor type with DVT as a major decision-making indicator for DUS. A primary analysis investigated the association between tumor pathology and preoperative DVT, and a secondary analysis investigated the development of DVT postoperatively. Confounding factors were defined and included in both analyses.Among 1478 patients, 751 had preoperative DUS and 35 (5%) had DVT. No significant difference in the odds of preoperative DVT was observed between patients having malignant glioma versus benign tumors (odds ratio [OR; 95% CI]: 1.68 [0.65, 4.35], P = 0.29), or metastatic tumors versus benign tumors (OR: 2.10; 95% CI: 0.75-5.89; P = 0.16). Among patients with negative preoperative DUS, 93 underwent postoperative evaluation and 20 (22%) were diagnosed with postoperative DVT. Malignant glioma or (OR: 1.69; 95% CI: 0.36-7.84; P = 0.50) metastatic tumors (OR: 1.84; 95% CI: 0.29-11.5; P = 0.52) were not associated with postoperative DVT versus benign tumors.Brain tumor pathology may not increase the risk for DVT and may not be a good indicator for the selection of patients for DVT screening with DUS. The incidence of DVT in selective preoperative DUS was similar to studies that performed DUS on all patients. Further studies across multiple institutions are needed to develop criteria for DUS in brain tumor surgery.Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.