脆弱和肾细胞癌：将全面的老年评估整合到共同的决策中

脆弱是一种以恢复能力和生理储备为特征的老年综合征，对老年人的预后和管理产生了重大影响，尤其是在手术和肿瘤学护理的背景下，在肾脏质量/肾细胞癌（RCC）的临床范围内，概述了脆弱的评估概述，并涉及临床临床癌症（RCC），诊断为诊断诊断的工作，诊断为工作。对文献进行了叙事回顾，重点是脆弱的定义，评估工具及其在老年肿瘤学中的应用，应用于RCC领域。相关研究涉及脆弱的预后价值，其对治疗结果的影响以及潜在的干预措施的相关研究。杂货是一个差的预后因素，可以影响局部和转移性RCC的管理决策。筛查工具，例如老年筛查工具8（G8）和迷你cog测试，可以帮助临床医生选择老年患者（即≥65岁），以进一步全面的老年评估（CGA），由专门的老年医生进行。 CGA提供了风险分层患者并指导随后的治疗途径的见解。因此，老年医生参与多学科肿瘤板，这是满足脆弱患者的复杂需求并优化临床结果的重要优先事项。在此，我们提出了一种专门的护理途径，作为在RCC中实施脆弱评估的第一步，用于RCC的临床实践和研究。Frailty已成为影响RCC老年患者的管理和结果的关键因素。老年医生参与诊断和治疗途径是一种务实的筛查方法和评估脆弱的方法，根据整体患者风险分层培养个性化的治疗决策。冻结，韧性和生理储备的下降，影响肾细胞电脑瘤的老年患者的治疗决策和成果。在这篇综述中，我们专注于务实的策略，以筛查涉嫌肾脏细胞癌的肾脏肿块的患者，年龄在65岁以上的肾脏肿瘤，以脆弱的和个性化的管理算法整合了与患者和肿瘤相关的因素以外的老年输入的个性化管理算法。

Frailty, a geriatric syndrome characterized by decreased resilience and physiological reserve, impacts the prognosis and management of older adults significantly, particularly in the context of surgical and oncological care.To provide an overview of frailty assessment in the management of older patients with a renal mass/renal cell carcinoma (RCC), focusing on its implications for diagnostic workup, treatment decisions, and clinical outcomes.A narrative review of the literature was conducted, focusing on frailty definitions, assessment tools, and their application in geriatric oncology, applied to the field of RCC. Relevant studies addressing the prognostic value of frailty, its impact on treatment outcomes, and potential interventions were summarized.Frailty is a poor prognostic factor and can influence decision-making in the management of both localized and metastatic RCC. Screening tools such as the Geriatric Screening Tool 8 (G8) and the Mini-COG test can aid clinicians to select older patients (ie, aged ≥65 yr) for a further comprehensive geriatric assessment (CGA) performed by dedicated geriatricians. The CGA provides insights to risk stratify patients and guide subsequent treatment pathways. As such, the involvement of geriatricians in multidisciplinary tumor boards emerges as an essential priority to address the complex needs of frail patients and optimize clinical outcomes. Herein, we propose a dedicated care pathway as a first key step to implement frailty assessment in clinical practice and research for RCC.Frailty has emerged as a crucial factor influencing the management and outcomes of older patients with RCC. Involvement of geriatricians in diagnostic and therapeutic pathways represents a pragmatic approach to screen and assess frailty, fostering individualized treatment decisions according to holistic patient risk stratification.Frailty, a decline in resilience and physiological reserve, influences treatment decisions and outcomes in elderly patients with renal cell carcinoma, guiding personalized care. In this review, we focused on pragmatic strategies to screen patients with a renal mass suspected for renal cell carcinoma, who are older than 65 yr, for frailty and on personalized management algorithms integrating geriatric input beyond patient- and tumor-related factors.