加速康复外科（ERAS）在腹部手术的术后管理中越来越受欢迎。已发表的数据表明，采用 ERAS 方案的患者的轻微和主要并发症较少，并强调医疗发病率（例如泌尿道和呼吸道感染）的降低。关于手术并发症的数据有限。该研究的目的是评估 ERAS 方案对术后并发症和住院时间的影响。此外，我们的目的是确定该方案对成本效益的影响。从 2016 年 1 月到 2022 年 12 月，进行了 532 例结直肠癌 (CRC) 结肠切除术。在一家三级医院对 18 岁及以上接受非紧急结直肠癌手术的患者队列进行了一项前瞻性观察性研究。分析了两组对术后并发症、住院时间和经济影响的影响：根据 ERAS 和非 ERAS 方案管理的患者。对两组进行倾向评分匹配分析。倾向评分匹配1:1后，每组共纳入71例患者，肿瘤类型、手术技术和手术方式等临床病理特征均衡。 ERAS 患者的感染并发症较少，术后住院时间较短 (p< 0.001)。特别是，吻合口裂开 (p=0.012) 和手术伤口感染 (p=0.029) 减少了 8.5%。对医疗并发症进行分析后，在尿路感染、肺炎、胃肠道出血或败血症方面没有发现统计学上的显着差异。 ERAS 方案比对照组更高效且更具成本效益，总体节省了 37,673.44 欧元。在三级医院实施择期结直肠手术加速康复方案具有成本效益，并且与术后并发症的减少相关并发症，尤其是感染性并发症。© 2024。Springer Nature Switzerland AG。

Enhanced Recovery After Surgery (ERAS) has become increasingly popular in the post-operative management of abdominal surgery. Published data suggest that patients on ERAS protocols have fewer minor and major complications, and highlight a reduction in medical morbidity (such as urinary and respiratory infections). Limited data is available on surgical complications. The aim of the study was to evaluate the impact of the ERAS protocol on post-operative complications and length of hospital stay. Furthermore, we aimed to determine the impact of this protocol on cost-effectiveness.From January 2016 to December 2022, 532 colectomies for colorectal cancer (CRC) were performed. A prospective observational study was conducted in a tertiary hospital on the cohort of patients, aged 18 years and older, operated on for non-urgent colorectal cancer. The impact on post-operative complications, hospital stay and economic impact was analysed in two groups: patients managed under ERAS and non-ERAS protocol. A propensity score-matching analysis was performed between the two groups.After propensity score matching 1:1, each cohort included 71 patients, and clinicopathological characteristics were well balanced in terms of tumour type, surgical technique and surgical approach. ERAS patients experienced fewer infectious complications and a shorter postoperative stay (p < 0.001). In particular, they had an 8.5% reduction in anastomotic dehiscence (p = 0.012) and surgical wound infections (p = 0.029). After analysis of medical complications, no statistically significant differences were identified in urinary tract infections, pneumonia, gastrointestinal bleeding or sepsis. ERAS protocol was more efficient and cost-effective than the control group, with an overall savings of 37,673.44€.The implementation of an enhanced recovery protocol for elective colorectal surgery in a tertiary hospital was cost-effective and associated with a reduction in post-operative complications, especially infectious complications.© 2024. Springer Nature Switzerland AG.