机器人辅助根治性前列腺切除术 (RARP) 在定位前列腺癌中的临床评估：系统评价和网络荟萃分析。
A clinical evaluation of robotic-assisted radical prostatectomy (RARP) in located prostate cancer: A systematic review and network meta-analysis.
发表日期：2024 Sep 25
作者：
Meng-Yao Xu, Na Zeng, Sheng Ma, Zi-Jin Hua, Si-Han Zhang, Ji-Cheng Xiang, Yi-Fan Xiong, Zhi-Yu Xia, Jian-Xuan Sun, Chen-Qian Liu, Jin-Zhou Xu, Ye An, Shao-Gang Wang, Qi Dong Xia
来源：
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
摘要：
前列腺癌（PCa）是影响男性生殖系统的常见恶性肿瘤，目前临床治疗中广泛接受的PCa手术类型主要有三种：开腹前列腺癌根治术（ORP）、腹腔镜前列腺癌根治术（LRP）和机器人辅助前列腺癌根治术。 RARP）。在这里，我们的目的是基于 PCa 的背景，评估 RARP 与 ORP 和 LRP 相比对 PCa 患者的临床效果，包括两个维度：肿瘤学结果（生化复发 (BCR) 和阳性手术切缘 (PSM)）和功能结果（泌尿系统）。网络荟萃分析 (NMA) 中的节制和勃起功能恢复）。于2024年1月7日对PubMed、Embase和Cochrane数据库进行了系统检索。纳入了4项随机对照试验（RCT）和72项非RCT。 RARP 对降低 BCR 和更好地恢复勃起功能显示出显着的积极作用，但三种 PSM 和尿失禁手术类型之间不存在显着差异。版权所有 © 2024 作者。由 Elsevier B.V. 出版。保留所有权利。
Prostate cancer (PCa) is a prevalent malignant tumor affecting the male reproductive system and there are mainly three widely accepted PCa surgery types in current clinical treatment: open radical prostatectomy (ORP), laparoscopic radical prostatectomy (LRP) and robot-assisted radical prostatectomy (RARP). Here, we aimed to evaluate the clinical effect of RARP for PCa patients compared with ORP and LRP based on the context of PCa encompass two dimensions: oncological outcomes (biochemical recurrence (BCR) and positive surgical margin (PSM)) and functional outcomes (urinary continence and recovery of erectile function) in this network meta-analysis (NMA). PubMed, Embase and Cochrane databases were systematically searched in January 7, 2024. 4 randomized controlled trials (RCTs) and 72 non-RCTs were included. RARP displayed significant positive effect on lower BCR and better recovery of erectile function but no significant differences existed among three surgery types for PSM and urinary continence.Copyright © 2024 The Authors. Published by Elsevier B.V. All rights reserved.